PMID: 11933133Apr 5, 2002Paper

Recuperative effect of Semecarpus anacardium linn. nut milk extract on carbohydrate metabolizing enzymes in experimental mammary carcinoma-bearing rats

Phytotherapy Research : PTR
Venugopal Sujatha, Panchanatham Sachdanandam

Abstract

Semecarpus anacardium Linn. of the family Anacardiaceae has many applications in the Ayurvedic and Siddha systems of medicine. We have tested the antitumour activity of Semecarpus anacardium nut extract against experimental mammary carcinoma in animals. As there is a direct relationship between the proliferation of tumour cells and the activities of the glycolytic and gluconeogenic enzymes, we studied changes in the activities of enzymes involved in this metabolic pathway in the liver and kidney. The enzymes investigated were glycolytic enzymes, namely hexokinase, phosphoglucoisomerase, aldolase and the gluconeogenic enzymes, namely glucose-6-phosphatase and fructose-1,6-biphosphatase in experimental rats. A significant rise in glycolytic enzyme activities and a simultaneous fall in gluconeogenic enzyme activities were found in mammary carcinoma bearing rats. Drug administration returned these enzyme activities to their respective control activities.

References

Sep 8, 1978·Science·I Fridovich
Jun 1, 1989·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·M M GrahamG L Abbott
Jan 1, 1988·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·A HennipmanG E Staal
Jan 1, 1985·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·R PaulL Kangas
Jan 1, 1987·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·A HennipmanG E Staal
May 1, 1963·Journal of Clinical Pathology·J E HORROCKSJ KING

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Citations

Mar 26, 2004·Cancer Chemotherapy and Pharmacology·Rama S RangaDamodaran Chendil
Nov 2, 2004·Planta·Srinivasan SowmyalakshmiDamodaran Chendil
Jan 26, 2012·Inflammopharmacology·Haseena Banu Hedayathullah KhanSachdanandam Panchanatham
May 7, 2009·Natural Product Research·P AnandakumarT Devaki
Oct 16, 2004·Journal of Cellular Biochemistry·Daniel LeclercRima Rozen
Oct 22, 2008·Biochemical and Biophysical Research Communications·Marina BiglKlaus Eschrich
Mar 14, 2007·Chemico-biological Interactions·Shanmugam ArulkumaranPanchanatham Sachdanandam
Mar 25, 2008·Chemico-biological Interactions·Dhanasekaran SugapriyaPanchanatham Sachdanandam
Apr 22, 2006·Chemico-biological Interactions·Krishnamurthy VeenaPanchanatham Sachdanandam
Mar 22, 2012·Journal of Dietary Supplements·Haseena Banu Hedayathullah KhanSachdanandam Panchanadham
Mar 7, 2018·BMC Complementary and Alternative Medicine·Preethi SoysaImali Ranathunga

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