Recurrence during pregnancy of a conservatively treated early-stage cervical squamous cell carcinoma

Fertility and Sterility
Pascale JadoulJacques Donnez

Abstract

To evaluate the safety of conservative management of early cervical cancer. Case report and analysis of literature guidelines. Academic teaching hospital. A 35-year-old, nulliparous woman treated by simple trachelectomy and pelvic lymphadenectomy for a well-differentiated, 12-mm squamous cell carcinoma infiltrating to a depth of 3 mm (stage Ib1) without lymphovascular space involvement. Follow-up. Recurrence and disease evolution. Sixteen months after surgery, at 32 weeks' gestation, a local recurrence of 5 cm in diameter was diagnosed, associated with pelvic and interaortocaval lymph node involvement. Despite extensive radiotherapy, chemotherapy, and radical surgery, disease progression could not be halted. We report a case of early-stage cervical cancer, conservatively treated by simple trachelectomy and lymphadenectomy, that recurred although none of the known risk factors for recurrence were initially present, and despite the fact that literature guidelines were followed.

References

Jan 15, 1983·American Journal of Obstetrics and Gynecology·J A Nisker, M Shubat
Jul 15, 1981·Cancer·P J DiSaia
May 12, 2005·Best Practice & Research. Clinical Obstetrics & Gynaecology·K Van CalsterenF Amant
May 31, 2007·Nature Clinical Practice. Oncology·Mario E Beiner, Allan Covens
Jul 9, 2008·Clinical Oncology : a Journal of the Royal College of Radiologists·J H Shepherd, D A Milliken
Aug 30, 2008·Gynecologic Oncology·Marie Plante

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.