Recurrence of perinatal death in Northern Tanzania: a registry based cohort study

BMC Pregnancy and Childbirth
Michael J MahandeRolv T Lie

Abstract

Perinatal mortality is known to be high in Sub-Saharan Africa. Some women may carry a particularly high risk which would be reflected in a high recurrence risk. We aim to estimate the recurrence risk of perinatal death using data from a hospital in Northern Tanzania. We constructed a cohort study using data from the hospital based KCMC Medical Birth Registry. Women who delivered a singleton for the first time at the hospital between 2000 and 2008 were followed in the registry for subsequent deliveries up to 2010 and 3,909 women were identified with at least one more delivery within the follow-up period. Recurrence risk of perinatal death was estimated in multivariate models analysis while adjusting for confounders and accounting for correlation between births from the same mother. The recurrence risk of perinatal death for women who had lost a previous baby was 9.1%. This amounted to a relative risk of 3.2 (95% CI: 2.2 - 4.7) compared to the much lower risk of 2.8% for women who had had a surviving baby. Recurrence contributed 21.2% (31/146) of perinatal deaths in subsequent pregnancies. Preeclampsia, placental abruption, placenta previa, induced labor, preterm delivery and low birth weight in a previous delivery with a survivi...Continue Reading

References

Dec 1, 1988·American Journal of Epidemiology·R SkjaervenL M Irgens
Sep 1, 1987·Paediatric and Perinatal Epidemiology·R SkjaervenT Bjerkedal
Feb 20, 2004·The New England Journal of Medicine·Pamela J SurkanSven Cnattingius
Jul 31, 2007·Paediatric and Perinatal Epidemiology·Allen J Wilcox
Jul 31, 2007·Paediatric and Perinatal Epidemiology·Puza P SharmaRussel S Kirby
Dec 18, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·M BlackS Bhattacharya
Jun 28, 2008·Archives of Gynecology and Obstetrics·Adi Y WeintraubArnon Wiznitzer
May 15, 2009·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Godfrey MbarukuStaffan Bergström
Aug 21, 2009·American Journal of Obstetrics and Gynecology·Darios GetahunSteven J Jacobsen
Nov 26, 2009·Obstetrics and Gynecology·Svein RasmussenKari Klungsøyr Melve
Jun 25, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·S BhattacharyaA Shetty
Aug 19, 2010·BMC Pregnancy and Childbirth·Abdoulaye Hama DialloUNKNOWN PROMISE-EBF Study Group
Sep 9, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Hamisu M SalihuAmina P Alio
May 17, 2011·PloS One·Victoria NankabirwaUNKNOWN PROMISE EBF Research Consortium
May 25, 2011·Early Human Development·Hamisu M SalihuAlfred K Mbah
Sep 16, 2011·PLoS Medicine·Mikkel Zahle OestergaardUNKNOWN United Nations Inter-Agency Group for Child Mortality Estimation and the Child Health Epidemiology Reference Group
Sep 22, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·E M AugustA P Alio
Dec 4, 2012·BMC Pregnancy and Childbirth·Blandina T MmbagaAnne Kjersti Daltveit
May 17, 2013·Bulletin of the World Health Organization·Fengxiu OuyangMario Merialdi

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Citations

Jan 23, 2016·BMC Pregnancy and Childbirth·J Frederik FrøenVicki J Flenady
Jul 17, 2013·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Kristoffer Brodwall

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