PMID: 9179686Mar 1, 1997Paper

Recurrence of primary superficial bladder cancer treated with prophylactic intravesical Tokyo 172 bacillus Calmette-Guérin: a long-term follow-up

International Journal of Urology : Official Journal of the Japanese Urological Association
T ShinkaT Ohkawa

Abstract

Long-term results after transurethral resection (TUR) and prophylactic intravesical Tokyo 172 bacillus Calmette-Guérin (BCG) therapy for primary superficial bladder cancer were analyzed by multivariate analysis, and factors affecting the recurrence of bladder tumors after this therapy were examined. One-hundred and forty-one consecutive patients with primary superficial bladder cancer who consulted the Department of Urology at Wakayama Medical College and affiliated hospitals between May 1985 and May 1990 were studied. Tokyo strain BCG was given intravesically (80 mg in 40 ml saline) weekly for 6 weeks. The 5-year cumulative recurrence-free rate by the Kaplan-Meier method was 0.702 in 141 patients with primary superficial bladder cancer. The 5-year recurrence-free function using the proportional hazard model was 0.743. Using the Cox proportional hazard model, variables that significantly contributed to recurrence after intravesical BCG included female sex, tumor size less than 1 cm in diameter, and T1 tumor stage. Patient age, tumor type, multiplicity, tumor grade, and concomitant carcinoma in situ did not contribute to recurrence. Long-term results showed that prophylactic intravesical Tokyo strain BCG after TUR for primary su...Continue Reading

References

Nov 1, 1991·Reviews of Infectious Diseases·B Styrt, B Sugarman
Jun 1, 1989·British Journal of Urology·T ShinkaT Ohkawa
Jul 1, 1985·The Journal of Urology·D L Lamm
Jan 1, 1983·Cancer Immunology, Immunotherapy : CII·R MandevilleN Rocheleau
Jun 1, 1984·The Journal of Urology·A Morales, A S Pang
Mar 1, 1995·American Journal of Reproductive Immunology : AJRI·K HiguchiH Okada
Jun 1, 1995·International Journal of Urology : Official Journal of the Japanese Urological Association·D L LammT Shinka

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Citations

Nov 30, 2010·World Journal of Urology·Alon Z WeizerJeffrey S Montgomery
Aug 23, 2000·The Journal of Urology·F Millán-RodríguezJ Vicente-Rodríguez
Dec 22, 1999·The Journal of Urology·F Millán-RodríguezJ Vicente-Rodríguez
Jun 28, 2008·Journal of Korean Medical Science·Sung Joon HongUNKNOWN Korean Urological Oncology Society
Jul 9, 2008·Scandinavian Journal of Urology and Nephrology·G JanckeS Jahnson

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