Recurrence patterns of intraductal papillary mucinous neoplasms of the pancreas on enhanced computed tomography

Journal of Computer Assisted Tomography
Jonathan LandaLawrence H Schwartz

Abstract

To characterize imaging features and findings in recurrent intraductal papillary mucinous neoplasms (IPMN); thereby reconciling the "field defect" theory with the appearance of recurrences distant from the resection margin. Computed tomography findings were reviewed in 89 patients who were resected with IPMN. At follow-up, the appearance of the pancreatic duct, features of recurrent masses, evidence of enhancement, calcifications, lymphadenopathy, and metastases were recorded. Fourteen (16%) of the 89 patients had evidence of recurrence. Nine (64%) of the 14 patients demonstrated evidence for local recurrence. Ten recurrent lesions were noted in 9 patients. Patients with recurrence demonstrated an increase of pancreatic ductal dilatation of 3.3 mm, whereas patients without recurrence either had no dilatation or dilatation which then decreased over time. Computed tomography findings suspicious for tumor recurrence include enlarging mass (either solid, cystic or both), progressive ductal dilatation, or extrapancreatic disease. There was a lack of correlation between margin status and location of recurrence within the pancreas consistent with the global field defect theory of IPMN.

References

Jan 1, 1996·Radiology·C ProcacciG F Pistolesi
Jun 24, 1998·Annals of Surgery·M A TalaminiH A Pitt
Oct 20, 1999·Journal of Hepato-biliary-pancreatic Surgery·M InagakiS Kasai
Apr 30, 2002·Gastrointestinal Endoscopy·James J Farrell, William R Brugge
Mar 26, 2003·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Michael G SarrPatrick C Freeny
Apr 11, 2003·Archives of Surgery·Carlos Fernández-del CastilloAndrew L Warshaw
May 29, 2004·Annals of Surgery·Taylor A SohnKeith D Lillemoe
Jan 28, 2006·Radiology·Dushyant V SahaniCarlos Fernandez-Del Castillo
Feb 25, 2006·AJR. American Journal of Roentgenology·Satomi KawamotoElliot K Fishman
Mar 7, 2006·Surgical Oncology·George H SakorafasGeorge Peros
Jan 9, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S GourgiotisS Germanos

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Citations

Mar 15, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Mohammad Al-HaddadJohn Dewitt
Mar 27, 2018·Gut·UNKNOWN European Study Group on Cystic Tumours of the Pancreas
Sep 19, 2019·Nature Reviews. Gastroenterology & Hepatology·Nadine C M van HuijgevoortMarc G Besselink

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