Recurrence rate and associated factors of borderline ovarian tumors in the south of Vietnam

The Journal of Obstetrics and Gynaecology Research
Tuan M VoThanh C Bui

Abstract

This study aimed to determine the recurrence rate and related risk factors of borderline ovarian tumors (BOT). We conducted a retrospective cohort study with 433 patients who were surgically treated for primary BOT at Tu Du Hospital from 11/2008 to 09/2015. We used the life table method to estimate the cumulative recurrence rate. We used the log-rank test and Cox proportional hazard model to determine recurrence-associated factors. Median follow-up time was 43 months (range: 3-105 months). Eighteen patients developed recurrence. The cumulative BOT recurrence rates at year 1, 2, 3 and 4 were 1.2% (95% confidence interval [CI] = 0.5-2.8), 3.0% (95% CI = 1.7-5.2), 4.6% (95% CI = 2.9-7.4), and 5.1% (95% CI = 3.2-8.0), respectively. In the final multivariate model, a higher recurrence rate was significantly associated with primary tumor stages (stage I vs stages II and III, hazards ratio [HR] = 4.44, 95% CI = 1.60-12.38), pre-operative tumor's capsule rupture (HR = 4.14, 95% CI = 1.78-9.64), and cystectomy (HR = 5.33, 95% CI = 1.43-19.91). The overall BOT recurrence rate in women in southern Vietnam was moderate. Primary tumor stage, capsule rupture, and cystectomy were main factors associated with BOT recurrence. Appropriate follow...Continue Reading

References

Apr 29, 1999·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G J RustinK Bertelsen
Sep 19, 2000·American Journal of Obstetrics and Gynecology·W H GotliebG Ben-Baruch
May 16, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G ZanettaC Mangioni
Oct 16, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G J RustinT Meyer
Mar 22, 2003·Annals of Oncology : Official Journal of the European Society for Medical Oncology·P MoriceD Castaigne
Jul 13, 2005·Gynecologic Oncology·Ali AyhanTurkan Kucukali
Oct 12, 2005·Gynecologic Oncology·Raffaele TinelliAntonio Malvasi
Dec 6, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P Morice
Feb 24, 2006·Annals of Surgical Oncology·Christophe PonceletEmile Daraï
Jul 29, 2008·International Journal of Cancer. Journal International Du Cancer·Ingiridur SkírnisdóttirLars Holmberg
Feb 11, 2012·Best Practice & Research. Clinical Obstetrics & Gynaecology·Claes Göran TropéBen Davidson
Oct 2, 2012·The Oncologist·Daniela FischerovaDavid Cibula
Mar 16, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Andreas du BoisUNKNOWN Arbeitsgmeinschaft Gynäkologische Onkologie (AGO) Study Group
May 30, 2015·Obstetrics & Gynecology Science·Kimio UshijimaKen Matsukuma
Sep 26, 2015·Journal of Gynecologic Oncology·Seok Ju SeongTaejong Song
May 4, 2016·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A du BoisP Harter
May 14, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Piotr SobiczewskiBeata Śpiewankiewicz
Dec 28, 2016·Virchows Archiv : an International Journal of Pathology·Steffen HauptmannStefanie Avril
Aug 18, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Xiaobing JiaoLirong Zhu

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Citations

Sep 16, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Hee-Jung JungJoo-Hyun Nam
Oct 2, 2021·Annals of Surgical Oncology·Giulio RicottaSébastien Gouy

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