Recurrence rates of basal cell carcinoma of the periocular skin: what to do with patients who have positive margins after resection

Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Kim N JebodhsinghJohn T Harvey

Abstract

To determine the recurrence rates of basal cell carcinoma of the periocular skin in patients who were in the following 3 groups after pathologic analysis: Mohs frozen sections (negative margins); permanent sections with positive tumor margins; and permanent sections with negative tumor margins at the time of primary surgical removal. The study is a retrospective chart review. We identified 385 patients who underwent surgery for basal cell carcinoma. The surgery was performed by a single surgeon between January 1, 1995 and January 1, 2005. The patients were divided into 3 groups: (i) Mohs frozen sections with margins negative for tumor; (ii) permanent sections with margins negative for tumor; (iii) permanent sections with margins positive for tumor. The recurrence rates of basal cell carcinoma were compared. The recurrence-free rate was 92% for the group that had had Mohs frozen-section, 87% for the group that had had permanent sections with negative margins, and 80% for the group that had had permanent sections with positive margins at 170 months follow-up time. We found that the only predictor of recurrence rate was younger age (hazards ratio (HR) = 0.97 95%; CI 0.94, 0.99; p = 0.021). The results showed a statistically signif...Continue Reading

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Citations

Feb 24, 2015·Clinics in Dermatology·Vivian T YinBita Esmaeli
Jul 24, 2018·Journal of Cutaneous Medicine and Surgery·Christian MurrayTeresa Petrella
Nov 27, 2019·The Journal of Dermatological Treatment·Kevin PhanAnousha Yazdabadi
Apr 12, 2017·Asia-Pacific Journal of Ophthalmology·Nora Silverman, Roman Shinder

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Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

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