Recurrent acute pulmonary embolism and paroxysmal atrial fibrillation associated with subclinical hyperthyroidism

International Journal of Cardiology
Salvatore PatanèClaudia Cimino

Abstract

Subclinical hyperthyroidism is an increasingly recognized entity that is defined as a normal serum free thyroxine and free triiodothyronine levels with a thyroid-stimulating hormone level suppressed below the normal range and usually undetectable. It has been reported that subclinical hyperthyroidism is not associated with coronary heart disease or mortality from cardiovascular causes but it is sufficient to induce arrhythmias including atrial fibrillation and atrial flutter. It has also been reported that increased factor X activity in patients with subclinical hyperthyroidism represents a potential hypercoagulable state. Elevated D-dimer levels have been reported in acute pulmonary embolism and it has also been reported that right ventricular overload and hypoxia in acute pulmonary embolism may lead to right ventricular myocardium injury reflected by elevated cardiac troponin levels too. We present a case of recurrent pulmonary embolism associated with subclinical hyperthyroidism, in an 81-year-old Italian woman. Also this case focuses attention on the importance of a correct evaluation of subclinical hyperthyroidism.

References

Apr 6, 2007·International Journal of Cardiology·Anna KaczyńskaPiotr Pruszczyk
Jun 27, 2008·International Journal of Cardiology·Salvatore PatanèGiuseppe Turiano
Dec 3, 2008·International Journal of Cardiology·Andrew J S Coats

❮ Previous
Next ❯

Citations

May 25, 2012·International Journal of Cardiology·Salvatore Patanè
May 1, 2009·International Journal of Cardiology·Annalisa LamariSalvatore Patanè
Aug 27, 2010·Journal of Thrombosis and Haemostasis : JTH·H-C LinJ-H Kang
Jan 5, 2010·International Journal of Cardiology·Salvatore PatanèMauro Sturiale
Jan 5, 2014·Journal of the American Heart Association·Erin M HaldJohn-Bjarne Hansen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.