journal cover

Recurrent alternative splicing isoform switches in tumor samples provide novel signatures of cancer

bioRxiv

Jul 4, 2014

E SebestyénE Eyras

Abstract

Cancer genomics has been instrumental to determine the genetic alterations that are predictive of various tumor conditions. However, the majority of these alterations occur at low frequencies, motivating the need to expand the catalogue of cancer signatures. Alternative pre-mRNA splicin...read more

Mentioned in this Paper

FBLN2 gene
Transcript
Pre-mRNA Splicing
Biochemical Pathway
MYH11 wt Allele
Neoplasms
RNA Splicing
Computer Software
The Cancer Genome Atlas
Subtype (Attribute)
26
13
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

RNA Splicing (Keystone)

The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Discover the latest research on RNA splicing and co-transcriptional splicing in this feed.

RNA Splicing

The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Discover the latest research on RNA Splicing here.

Exon Skipping

Exon skipping is a method of RNA splicing used when a mutation occurs in the genes of exons. It is regulated largely by the use of antisense oligonucleotides that mask the mutated gene and allow the cellular machinery to skip over it. Exon skipping is being investigated as a therapeutic option for some diseases. Here is the latest research on exon skipping.

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Alternative splicing

Alternative splicing a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Here is that latest research.

Cancer Genomics

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest research here.

Human Tumor Atlas (Preprints)

The Human Tumor Atlas is a collaborative project that uses detailed maps of a variety of cancers to investigate cancer development, metastasis, and treatments. Discover the latest preprints from the Human Tumor Atlas here.

Cancer Genomics (Preprints)

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest preprints here.

Cancer Genomics (Keystone)

Cancer genomics approaches employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest research using such technologies in this feed.

Spliceosome

Spliceosomes are massive RNA protein macromolecules that are cellular machinery involved in the splicing and removal of the non-coding segments of DNA and the ligation of coding segments, exons. Discover the latest research on spliceosomes here.

© 2020 Meta ULC. All rights reserved

Recurrent alternative splicing isoform switches in tumor samples provide novel signatures of cancer

bioRxiv

Jul 4, 2014

E SebestyénE Eyras

PMID: 990006908

DOI: 10.1101/006908

Abstract

Cancer genomics has been instrumental to determine the genetic alterations that are predictive of various tumor conditions. However, the majority of these alterations occur at low frequencies, motivating the need to expand the catalogue of cancer signatures. Alternative pre-mRNA splicin...read more

Mentioned in this Paper

FBLN2 gene
Transcript
Pre-mRNA Splicing
Biochemical Pathway
MYH11 wt Allele
Neoplasms
RNA Splicing
Computer Software
The Cancer Genome Atlas
Subtype (Attribute)
26
13

Similar Papers Found In These Feeds

Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/recurrent-alternative-splicing-isoform-switches/990006908