Recurrent cerebral embolism in a familial amyloid polyneuropathy patient who received partial liver transplantation from a living donor

Internal Medicine
M OwaShu-Ichi Ikeda

Abstract

Cerebral embolism in relation to cardiac amyloidosis has not been widely noted. A 47-year-old woman who had been suffering from familial amyloid polyneuropathy (FAP) for 7 years was treated with partial liver transplantation from a living donor and her early postoperative course was uneventful. During the 391st to 613th postoperative day she experienced recurrent cerebral infarctions, but clinical examinations revealed no disorders capable of producing cerebral embolism. At autopsy splenic infarction and intracardiac thrombi adhering to the mitral valve and left atrium were found, and these areas showed severe amyloid deposition. Amyloid heart is considered to be one possible cause of systemic embolism.

Citations

Jul 1, 2003·Expert Review of Neurotherapeutics·Shu-Ichi IkedaYasuhiko Hashikura
Apr 1, 2005·Journal of Clinical Neurology·Kyung-Hee ChoJong S Kim
May 16, 2012·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·Michitaka NakagawaShu-ichi Ikeda
Feb 13, 2008·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·Michiyo YamanoHiroaki Matsubara
Dec 19, 2017·Experimental and Therapeutic Medicine·Xu-Dong ZhangYi-Ning Wang

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