PMID: 3771004Oct 1, 1986Paper

Recurrent cerebral embolism in cardiac amyloidosis

International Journal of Cardiology
H E Bøtker, O B Rasmussen

Abstract

Cardiac involvement is common in systemic amyloidosis. The most frequent cardiovascular manifestations are congestive heart failure and arrhythmias. Embolic complications often occur after the onset of these symptoms. We report a 46-year-old woman with systemic amyloidosis, who sustained two middle cerebral artery strokes and shortly after developed symptoms of cardiac and renal failure with a rapid fatal course. Postmortem findings revealed mural thrombi in the left atrium as the source of embolism to the brain, to the spleen, and to the left kidney. As no evidence of congestive heart failure or arrhythmias was found in the beginning, the mechanism of mural thrombosis was probably an alteration in the thrombogenicity of the endocardium itself.

References

Oct 1, 1970·Archives of Internal Medicine·R F BarthW C Roberts
Jul 1, 1983·The American Journal of Cardiology·W C Roberts, B F Waller
Jul 1, 1981·Neurology·G P RiceG P Wysocki
Jan 1, 1981·Circulation·A G Siqueira-FilhoE R Giuliani

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Citations

Nov 7, 2007·Circulation·DaLi FengKyle W Klarich
Feb 26, 2020·BMJ Case Reports·Suleiman SuleimanDavid Moore
Dec 19, 2017·Experimental and Therapeutic Medicine·Xu-Dong ZhangYi-Ning Wang
Jan 1, 1990·Critical Reviews in Oncology/hematology·R A Kyle, M A Gertz

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