PMID: 6320421Dec 29, 1983

Recurrent familial hyperparathyroidism. A propos of 7 adenomas in 3 members of the same family. Review of the literature

La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
P DouryP Dano

Abstract

Over a period of 23 years, 3 members of a family of 5 presented with 7 parathyroid adenomas (4 in the first case, 2 in the second case, 1 in the third case). Excision of each adenoma, with systematic pre-operative assessment of the remaining parathyroid tissue, led to complete clinical and laboratory cure of each episode. The delay in the appearance of recurrence was between 3 and 9 years. After reviewing the literature, the authors stress the importance, in any case of hyperparathyroidism, of routinely investigating the serum calcium levels in members of the patient's family, especially if the patient is young and if he has had several episodes or multiglandular involvement in one episode. The authors discuss the literature concerning recurrent familial hyperparathyroidism with endocrine polyadenomatosis and the "hypercalcaemia-hypocalciuria" syndrome.

Related Concepts

Adenoma, Trabecular
Calcium
Hyperparathyroidism
Parathyroid Adenoma
Relapse

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