Recurrent intracardiac thrombosis as an unusual manifestation of inherited thrombophilia

International Journal of Cardiology
Sandra OhlenforstBernd Pötzsch

Abstract

Patients with inherited thrombophilia are at high risk for the development of venous thrombosis that manifests mainly as deep venous thrombosis of the legs and/or pulmonary embolism. We report spontaneous right-sided intracardiac thrombosis in a young man as an unusual manifestation of inherited thrombophilia. The diagnosis of thrombophilia was confirmed by demonstration of the prothrombin-G20210A-mutation in the homozygous state. A second spontaneous intracardiac thrombosis occurred 3 years after discontinuation of oral anticoagulant treatment. This indicates the high risk for recurrence in patients developing intracardiac thrombosis in the absence of an underlying cardiac disease and warrants long-term oral anticoagulant treatment.

References

Jul 29, 1998·Cardiology in the Young·B KohlhaseU Nowak-Göttl
Mar 5, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Nithima ChaowalitPatricia A Pellikka
May 19, 2005·JAMA : the Journal of the American Medical Association·Sverre C ChristiansenFrits R Rosendaal

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Citations

Dec 27, 2011·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Pradeep VaideeswarMegha Harke
Jul 9, 2016·International Journal of Cardiology·G PizziV Battaglia

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