Recurrent medulloblastoma: frequency of tumor enhancement on Gd-DTPA MR imaging

AJR. American Journal of Roentgenology
N RollinsF Sklar

Abstract

Thirty-two children with medulloblastoma were evaluated postoperatively with conventional and gadolinium-enhanced MR imaging. Eleven patients had abnormal cranial MR studies; nine of these had recurrent tumor. In six patients recurrent tumor enhanced with Gd, while in the other three patients recurrent tumor did not enhance. The remaining two patients had areas of abnormal Gd enhancement that were caused by radiation-induced breakdown of the blood-brain barrier rather than by recurrent tumor. This study shows that not all recurrent medulloblastoma enhances and that the absence of Gd enhancement does not necessarily indicate the absence of recurrent tumor.

Citations

Nov 27, 1998·Pediatric Neurology·L A O'TuamaS T Treves
Nov 15, 2003·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Kelly K Koeller, Elisabeth J Rushing
Aug 10, 2013·Neuroimaging Clinics of North America·Lara A Brandão, Tina Young Poussaint
Oct 1, 1992·Clinical Imaging·D P MuellerW T Yuh
Apr 1, 1992·Journal of Child Neurology·F H TomlinsonR V Groover
Dec 6, 2018·Topics in Magnetic Resonance Imaging : TMRI·Guilherme de Souza E CassiaZoltan Patay
Nov 8, 2018·Neuro-oncology Practice·Mariam S AboianSoonmee Cha

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