Recurrent nightmares and disorders of arousal in temporal lobe epilepsy

Brain Research Bulletin
Rosalia Silvestri, Edward Bromfield

Abstract

Sleep is known to be severely altered in temporal lobe epilepsy (TLE). Furthermore, sleep deprivation is one of the key factors contributing to cognitive deficits and drug resistance in TLE. In the past, "non-ictal" parasomnias, as well as parasomnia-like nocturnal episodes ultimately diagnosed as seizures, have been documented in epileptic patients. However, recurrence of possibly "ictal" parasomnias in TLE has not been adequately appreciated. Through questionnaires and diaries distributed to TLE patients and their families in a tertiary center for epilepsy, 20 out of 168 patients seen in the last 2 years have been identified as, probands and extensively recorded during sleep. Patients presented with confusional arousals were 16, 14 with nightmares, and 2 with sleep walking episodes. Episodes (25) corresponding to clinical or subclinical seizures have been video-polygraphically recorded in 10/20 patients. Therapy optimization, pharmacological or surgical, resolved the episodes in 17/20 patients. A better seizure control with improved quality of life can be achieved by increasing and extending the practice of nocturnal recording in TLE patients.

References


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Citations

Jul 10, 2007·Current Neurology and Neuroscience Reports·Alcibiades J Rodriguez
Mar 15, 2011·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Madeleine Grigg-Damberger, Frank Ralls
Apr 3, 2012·European Journal of Pediatrics·Peter WeberAlexandre Niklaus Datta
Jun 24, 2010·Epilepsy Research·Raffaele Manni, Michele Terzaghi
Aug 20, 2008·Pediatric Annals·Madeliene Grigg-Damberger
Jul 31, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·N N TrajanovicA Ong
Feb 6, 2014·Sleep·Geneviève Robert, Antonio Zadra
Mar 23, 2019·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Amir FattahiMohammad Nouri

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