PMID: 6538119Jan 1, 1984Paper

Recurrent nocturnal asthma after bronchoprovocation with Western Red Cedar sawdust: association with acute increase in non-allergic bronchial responsiveness

Clinical Allergy
D W CockcroftG D Werner

Abstract

Recurrent nocturnal asthma following a single exposure to Western Red Cedar sawdust was documented by measurements of peak flow rates in two sensitized subjects. The nocturnal asthma followed a dual asthmatic response in the first subject and a late (non-immediate) asthmatic response in the second. Both subjects developed a 10-fold reduction in the dose of histamine required to decrease the FEV1 by 20%. This cedar-induced increase in non-specific bronchial reactivity was maximal at the time of the recurrent nocturnal asthma, and persisted after nocturnal asthma had ceased and after FEV1 had returned to normal. We hypothesize that the enhanced non-specific bronchial reactivity which occurs following late asthmatic responses to bronchial challenge is the cause of recurrent nocturnal asthma following single exposure to a sensitizing agent.

References

Dec 1, 1975·The Journal of Allergy and Clinical Immunology·J B Richardson, T Bouchard
Sep 1, 1979·The Journal of Allergy and Clinical Immunology·R C BoucherJ C Hogg
Mar 1, 1978·Clinical Allergy·A SiracusaG Abbritti
Aug 1, 1979·Australian and New Zealand Journal of Medicine·R D HamiltonJ H Alpers
May 1, 1979·The Journal of Allergy and Clinical Immunology·R C AndertonF E Hargreave
May 1, 1979·Clinical Allergy·A J TaylorJ Pepys
Nov 1, 1977·Clinical Allergy·D W CockcroftF E Hargreave
Jan 1, 1979·The Journal of Allergy and Clinical Immunology·S LamM Yeung
Feb 1, 1979·The Journal of Allergy and Clinical Immunology·P A Eggleston
Apr 1, 1977·British Journal of Diseases of the Chest·T J Clark, M R Hetzel
Aug 1, 1977·The Journal of Allergy and Clinical Immunology·M M MillerR Patterson
May 1, 1977·Clinical Allergy·D W CockcroftF E Hargreave
Oct 1, 1975·British Journal of Diseases of the Chest·M K Benson
Dec 1, 1980·The Journal of Allergy and Clinical Immunology·D W CockcroftF E Hargreave

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Citations

May 16, 1998·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·J P SeeryA K Datta
Nov 11, 1998·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Y Y KohK U Min
Jan 1, 1991·Annals of the New York Academy of Sciences·G E D'Alonzo, M H Smolensky
Jan 1, 1995·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·S K Chhabra
Jan 1, 1988·Annals of the New York Academy of Sciences·P M O'Byrne
Sep 1, 1992·The Journal of Allergy and Clinical Immunology·J B WempeG H Koëter
Sep 1, 1995·American Journal of Industrial Medicine·A SiracusaM Chan-Yeung
Sep 29, 2007·Advanced Drug Delivery Reviews·Michael H SmolenskyAlain E Reinberg

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