Recurrent ovarian cancer metastatic to the sternum, costae, and thoracic wall after prolonged treatment with platinum-based chemotherapy: a case report and review of the literature

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
G PavlakisP Papasavas

Abstract

Sternal and costal metastases from ovarian cancer are extremely rare. We present here a case of a 47-year-old woman with thoracic wall metastasis from serous-papillary ovarian carcinoma that occurred 3 years after the initial diagnosis, although the patient had received various regimens of intense platinum-based chemotherapy. Special emphasis is given to the effects of alkylating agents, such as cisplatin and carboplatin, on the pattern of tumor spread. We also discuss the possible mechanisms through which the biologic and metastatic behavior of this tumor is expressed.

References

May 16, 1990·Journal of the National Cancer Institute·H HenningsS H Yuspa
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Jun 28, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C A MonteroJ Ramirez
Apr 30, 2003·Abdominal Imaging·C M ParkH J Choi

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Citations

May 12, 2012·Surgery Today·Sotirios MoraitisGeorgios Pechlivanides
Apr 1, 2010·Nuclear Medicine and Molecular Imaging·Myung-Hee SohnChang-Yeol Yim
Dec 7, 2010·Acta Clinica Belgica·D TestelmansK Nackaerts
Jul 1, 2011·Clinical Nuclear Medicine·Linh HoHeidi Wassef

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