Recurrent pericarditis in children and adolescents: a multicentre cohort study

Journal of Cardiovascular Medicine
Massimo ImazioAlberto Martini

Abstract

Limited data are available about recurrent pericarditis in children. We sought to explore contemporary causes, characteristics, therapies and outcomes of recurrent pericarditis in paediatric patients. A multicentre (eight sites) cohort study of 110 consecutive cases of paediatric patients with at least two recurrences of pericarditis over an 11-year period (2000-2010) [median 13 years, interquartile range (IQR) 5, 69 boys]. Recurrences were idiopathic or viral in 89.1% of cases, followed by postpericardiotomy syndrome (9.1%) and familial Mediterranean fever (0.9%). Recurrent pericarditis was treated with nonsteroidal anti-inflammatory drugs (NSAIDs) in 80.9% of cases, corticosteroids in 64.8% and colchicine was added in 61.8%. Immunosuppressive therapies were administered in 15.5% of patients after subsequent recurrences. After a median follow-up of 60th months, 528 subsequent recurrences were recorded (median 3, range 2-25). Corticosteroid-treated patients experienced more recurrences (standardized risk of recurrence per 100 person-years was 93.2 for patients treated with corticosteroids and 45.2 for those without), side effects and disease-related hospitalizations (for all P < 0.05). Adjuvant therapy with colchicine was assoc...Continue Reading

References

Feb 1, 1986·Journal of the American College of Cardiology·N O Fowler, A D Harbin
May 4, 1968·British Medical Journal·J Robinson, W Brigden
Nov 1, 1995·Journal of the American College of Cardiology·R MarcolongoC Agostini
Sep 18, 1998·Journal of Pediatric Gastroenterology and Nutrition·T A Sentongo, D A Piccoli
Nov 21, 2002·Pharmacology & Therapeutics·Heike SchäckeKhusru Asadullah
Aug 23, 2003·Journal of the American College of Cardiology·Marja RaatikkaEero V Jokinen
Jul 11, 2006·The American Journal of Cardiology·Antonio BrucatoDavid H Spodick
Dec 21, 2006·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·R Dalla PozzaH Netz
Sep 11, 2007·The American Journal of Cardiology·Massimo ImazioRita Trinchero
Oct 1, 1992·Trends in Endocrinology and Metabolism : TEM·A Giustina, W B Wehrenberg
Aug 5, 2008·International Journal of Cardiology·Massimo ImazioYehuda Adler
Feb 24, 2010·Circulation·Massimo ImazioYehuda Adler
Jun 30, 2011·Pediatric Emergency Care·Savithiri RatnapalanLee Benson
Sep 8, 2012·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Kevin W BaszisAkaluck Thatayatikom
Sep 3, 2013·The New England Journal of Medicine·Massimo ImazioUNKNOWN ICAP Investigators
Dec 18, 2014·The New England Journal of Medicine·Martin M LeWinter

❮ Previous
Next ❯

Citations

Nov 29, 2016·Hospital Practice·Dario CelentaniFiorenzo Gaita
Jul 27, 2017·Journal of Cardiovascular Medicine·Kubra OzturkZelal Ekinci
Nov 13, 2018·Journal of Cellular Physiology·Aldo Bonaventura, Fabrizio Montecucco
Dec 5, 2018·Cardiology in the Young·Moises Rodriguez-GonzalezAna Castellano-Martinez
Nov 18, 2018·Current Opinion in Cardiology·Matthew J O'Connor
Jan 3, 2019·Pediatrics in Review·Hari TunuguntlaSusan W Denfield
Nov 12, 2019·Expert Review of Cardiovascular Therapy·Alessandro AndreisGaetano Maria de Ferrari
Jun 16, 2018·Current Cardiology Reports·Giacomo EmmiAntonio Brucato
Jul 20, 2018·Internal and Emergency Medicine·Antonio BrucatoAllan L Klein
Oct 18, 2019·Yeungnam University Journal of Medicine·Ju Hee ShinHee Joung Choi
Apr 9, 2020·Journal of Cardiovascular Pharmacology·Eduardo Thadeu de Oliveira CorreiaEvandro Tinoco Mesquita
Apr 11, 2018·Internal and Emergency Medicine·Antonio BrucatoDomenico Prisco
Jun 21, 2020·Current Cardiology Reports·Enrico TombettiCarla Carnovale
Nov 5, 2019·Frontiers in Pediatrics·Enrico TombettiRolando Cimaz
Jan 1, 2018·Current Otorhinolaryngology Reports·Charles A Dinarello
Nov 28, 2020·Journal of the American College of Cardiology·Flora L SigvardtChristian Madelaire
Mar 13, 2021·Frontiers in Pharmacology·Hana MalcovaRudolf Horvath
Aug 2, 2020·Jornal de pediatria·Stasa KrasicVladislav Vukomanovic
May 8, 2020·Trends in Cardiovascular Medicine·Giuseppe LopalcoFlorenzo Iannone
Jul 29, 2021·Current Cardiology Reports·Emanuele BizziAntonio Brucato

❮ Previous
Next ❯

Software Mentioned

MedCalc
SPSS Statistics

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Nederlands tijdschrift voor geneeskunde
C A Hoefnagel, E H Nauta
Transactions of the Association of American Physicians
S M WolffD W Alling
© 2021 Meta ULC. All rights reserved