Recurrent pleomorphic adenoma: results of surgical treatment

Annals of Surgical Oncology
Marc MakeieffBernard Guerrier

Abstract

Recurrent parotid pleomorphic adenoma surgery increases the risk of facial nerve injury, and there is also a risk of ulterior recurrence. Postoperative results from 62 consecutive patients operated for recurrent pleomorphic adenoma were analyzed. It was the first recurrence for 49 patients (79%), the second or more for 13 patients (21%). Total parotidectomy was performed in 69.4% of cases. Skin resection was performed in 47 patients (75.8%). Resection of a facial nerve branch was performed in seven patients (11.3%). Pathologic examination findings revealed carcinoma ex pleomorphic adenoma in 10/62 cases (16.1%) and microscopic multinodular disease in 39 patients (62.9%). Nine patients had preoperative facial palsy, 95% had postoperative facial paralysis ≥ grade II (House-Brackmann scale), and 11.3% still had ≥ grade III facial palsy after 1 year. Six patients developed another recurrence after our intervention (9.68%). Moreover, carcinoma was discovered after a new intervention in 40% of these patients. Initial partial parotid surgery [hazard ratio (HR) = 8.477, P = 0.008], microscopic multinodular recurrent disease (HR = 11.717, P = 0.005), and ≥ 1 recurrence number (HR = 10.608, P = 0.01) were associated with increased risk o...Continue Reading

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Citations

Jan 7, 2014·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·P JardelJ Thariat
Jul 22, 2014·Case Reports in Otolaryngology·Pierre PhilouzeMarc Poupart
Dec 3, 2013·Journal of Maxillofacial and Oral Surgery·F RiffatP Jani
Mar 10, 2011·Annals of Surgical Oncology·Poramate Pitak-ArnnopNiels Christian Pausch
Dec 3, 2013·American Journal of Otolaryngology·Poramate Pitak-Arnnop
Jul 3, 2013·The British Journal of Oral & Maxillofacial Surgery·Cyrus KerawalaJim McCaul
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Jul 22, 2014·The Laryngoscope·Konstantinos MantsopoulosHeinrich Iro
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Apr 24, 2016·Journal of Surgical Case Reports·Simon GoldieIan Swain
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Oct 30, 2016·Journal of Surgical Oncology·Yasmin Abu-GhanemRaphael Feinmesser
Mar 29, 2014·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Huawei LiuMin Hu
Mar 19, 2020·Head & Neck·Matthijs H ValstarMark McGurk
Nov 15, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Laura Mc LoughlinOrla Young

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