PMID: 9524032Apr 2, 1998Paper

Recurrent scleritis in lepromatous leprosy

Australian and New Zealand Journal of Ophthalmology
A PoonP McKelvie

Abstract

Recurrent immune-mediated scleritis after adequate treatment of leprosy is not well documented in the literature. We describe an Australian resident with unilateral intra-ocular lepromatous leprosy who had persistent non-infectious scleritis. A man of Anglo-Indian ancestry initially presented with lepromatous leprosy and unilateral ocular involvement. The affected eye had an interstitial keratitis and a granulomatous anterior uveitis that responded to antileprotics and anti-inflammatory agents. Despite systemic cure with triple antileprotic therapy, he developed recurrent scleritis that required multiple scleral patch grafts for scleral thinning and, subsequently, an enucleation. Histology failed to demonstrate persistent infection, rather a chronic non-granulomatous scleritis, which was probably immune mediated. This case demonstrates an ocular complication of leprosy that is infrequently reported. Patients with ocular involvement by leprosy are at risk of developing recurrent scleritis despite systemic cure with antileprotics.

Citations

Oct 24, 2000·International Journal of Dermatology·A M Klioze, F A Ramos-Caro
Jun 22, 2005·Survey of Ophthalmology·Narciss OkhraviSusan Lightman

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