PMID: 8939393Sep 1, 1996Paper

Recurrent septicaemia in a neutropenic patient with typhlitis

Clinical and Laboratory Haematology
S SadullahP G Cachia

Abstract

We report a case where life threatening gram negative sepsis developed in a patient with CLL in association with post chemotherapy neutropenia on three occasions. Bacterial typhlitis or neutropenic enterocolitis, which is a well described entity of bowel necrosis seen in immunosuppressed patients, was demonstrated at colonoscopy and was the probable portal of entry of micro-organisms. After spontaneous resolution of the typhlitis, further chemotherapy has been given without recurrent sepsis. Typhlitis should be considered as a cause of recurrent septicaemia in neutropenic patients.

Citations

Jun 11, 2005·European Journal of Haematology·Marcus GorschlüterAxel Glasmacher
Sep 17, 2008·Gastroenterology Research and Practice·P E T ArkkilaM-L Karjalainen-Lindsberg
Feb 16, 2000·Bone Marrow Transplantation·L BoggioJ N Winter
Nov 7, 2019·World Journal of Gastrointestinal Pathophysiology·Rong Xia, Xuchen Zhang
Jul 3, 2021·Medicina·Giuseppe BertozziRaffaele La Russa

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