PMID: 8583109Dec 1, 1995Paper

Recurrent Sweet's syndrome in reactivated Crohn's disease

Journal of Clinical Gastroenterology
G C ActisG Verme

Abstract

A 50-year-old woman developed an acute febrile dermatosis on two occasions concurrently with recurrent Crohn's disease of the colon. Based on the presence of painful erythematous plaques on both hands and forearms, on the leukocytosis with excess bands in peripheral blood, on the histology showing dermal infiltration by mature granulocytes, and on the prompt response to steroids, the diagnosis was made of Sweet's syndrome associated with Crohn's disease. Sweet's syndrome is thought to be a hypersensitivity reaction that leads to parainflammatory (e.g., infections, autoimmune disorders, vaccinations) and paraneoplastic (myeloproliferative disorders, solid malignancy) associations, with a frequency of 10-30%. The association of Sweet's syndrome with Crohn's disease is very rare, but the gastroenterologist should readily differentiate it; it is important to be aware that such patients may have a nonspecific elevated activity index owing to the underlying dermatosis.

Citations

Jul 30, 2005·Clinical & Developmental Immunology·Erina N FosterThomas P Prindiville
Jun 12, 2004·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·O A PaoluziP Paoluzi
Aug 2, 2000·Gastrointestinal Endoscopy·H YuchiT Eto
Jun 10, 2011·Expert Review of Gastroenterology & Hepatology·Giovanni C ActisIan R Mackay
Oct 13, 2001·Diseases of the Colon and Rectum·A RappaportE Dolev
Apr 2, 2019·Frontiers in Immunology·Michael S Heath, Alex G Ortega-Loayza
Apr 24, 2021·Journal of Crohn's & Colitis·Joseph SleimanFlorian Rieder

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.