Recurrent urticaria and reduced diamine oxidase activity

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
M H LessofR H Dowling

Abstract

An abnormal metabolism of histamine has been suspected in urticaria and the role of diamine oxidase (DAO: histaminase) is therefore of interest. We have studied DAO activity in plasma and jejunal biopsy material and have measured the post-heparin DAO release in 11 control subjects and nine with recurrent urticaria, three of whom had had concurrent episodes of abdominal pain. Two of the nine urticaria subjects had only a minimal rise in plasma DAO activity after heparin, three had a response which was at the lower end of the normal range, and four were normal. In four out of five cases in which jejunal biopsy activity was obtained, there was concordance between mucosal DAO activity and the post-heparin plasma DAO response. Those with abdominal symptoms had abnormally low mucosal DAO activity and the subject who was most severely affected had proven episodes of small bowel oedema.

References

Dec 1, 1977·Clinical and Experimental Dermatology·S YamamotoM W Greaves
Jan 1, 1989·Biochemical Pharmacology·L D'AgostinoG Mazzacca
Feb 28, 1987·British Medical Journal·R M Berrington, M Varnam
May 1, 1988·Allergy·G Ionescu, R Kiehl
Jul 1, 1980·The Journal of Clinical Investigation·G D LukS B Baylin
Jan 1, 1965·Scandinavian Journal of Clinical and Laboratory Investigation·K ROOS
Nov 1, 1961·Archives of Biochemistry and Biophysics·T OKUYAMA, Y KOBAYASHI

❮ Previous
Next ❯

Citations

Oct 10, 2003·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Sophia C JansenAnthony E J Dubois
Feb 3, 1999·Annals of the New York Academy of Sciences·M RaithelE G Hahn
Mar 3, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G F Clough, M K Church
May 30, 2013·Annals of Dermatology·Hee Jin ChoCheol Heon Lee
May 20, 2015·Allergologia et immunopathologia·A DaschnerC Cuéllar
Dec 5, 2008·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Imke ReeseThomas Werfel
Jan 13, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B BunselmeyerR Brehler
Nov 30, 2013·Allergy·S SmolinskaL O'Mahony
Oct 16, 2015·Clinical and Translational Allergy·Isabel J SkypalaC Venter
Feb 26, 2013·Allergology International : Official Journal of the Japanese Society of Allergology·Alvaro DaschnerCarmen Cuéllar
Oct 21, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·F SiebenhaarM Maurer
Feb 13, 2015·Anais Brasileiros De Dermatologia·Paulo Ricardo CriadoVitor Manoel Silva dos Reis
Aug 5, 2018·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Asya V KudryavtsevaPetra Staubach
Jan 1, 1991·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M H Lessof
Jul 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B R MacDonald, D A Robertson
Dec 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·F WantkeR Jarisch
Dec 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G KannyJ L Gueant
Oct 28, 2019·Analytical and Bioanalytical Chemistry·Oriol Comas-BastéM Carmen Vidal-Carou
May 11, 2007·The American Journal of Clinical Nutrition·Laura Maintz, Natalija Novak
Aug 23, 2020·Biomolecules·Oriol Comas-BastéMaría Del Carmen Vidal-Carou
Sep 16, 1996·The Medical Journal of Australia·R J MullinsR T Dobson
May 1, 2021·Nutrients·Wojciech NazarAgnieszka Szlagatys-Sidorkiewicz
Jul 3, 2021·Nutrients·Martin HrubiskoMartin Wawruch

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
G KannyJ L Gueant
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
B R MacDonald, D A Robertson
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
F WantkeR Jarisch
© 2021 Meta ULC. All rights reserved