Recurrent venous thromboembolism while on anticoagulant therapy

Blood Reviews
Jecko Thachil

Abstract

There has been immense progress in the management of venous thromboembolism in recent years with increased awareness and adequate thromboprophylaxis proving successful in reducing the morbidity and mortality associated with this condition. One of the commonest complications of an initial venous thrombosis is the development of recurrent thrombosis. Unlike in the case of the first clot, the diagnosis and management of the recurrent episode remain a difficult issue. Even more challenging is the clinical situation where a new thrombus develops while the patient is being treated with anticoagulant medication for a previous clot. The clinical approach and management of these patients are complex, and require understanding of the differences in thrombus development in the different clinical circumstances.

References

Aug 15, 1992·Annals of Internal Medicine·M H Rosove, P M Brewer
Nov 9, 1995·The New England Journal of Medicine·P HillmenJ V Dacie
Apr 13, 1995·The New England Journal of Medicine·M A KhamashtaG R Hughes
Jul 27, 2000·Current Opinion in Pulmonary Medicine·M V Huisman
Jul 11, 2003·The New England Journal of Medicine·Agnes Y Y LeeUNKNOWN Randomized Comparison of Low-Molecular-Weight Heparin versus Oral Anticoagulant Therapy for the Prevention of Recurrent Veno
Dec 4, 2003·JAMA : the Journal of the American Medical Association·Alan S GoDaniel E Singer
Dec 16, 2003·Arthritis and Rheumatism·Doruk ErkanRonald A Asherson
Apr 16, 2004·Seminars in Thrombosis and Hemostasis·Jeanine M WalengaMamdouh Bakhos
Jun 17, 2004·Seminars in Vascular Medicine·P PrandoniA Girolami
Sep 15, 2004·Archives of Internal Medicine·Lori-Ann LinkinsClive Kearon
Jan 27, 2005·Journal of Thrombosis and Haemostasis : JTH·M Den HeijerR Clarke
Apr 7, 2005·JAMA : the Journal of the American Medical Association·Russell P RotherMark T Gladwin
Nov 24, 2005·Hematology·Thomas L Ortel
Mar 2, 2006·JAMA : the Journal of the American Medical Association·Wendy LimJohn W Eikelboom
Sep 21, 2006·Blood·Bill GiannakopoulosSteven A Krilis
Oct 27, 2006·The New England Journal of Medicine·Gualtiero PalaretiUNKNOWN PROLONG Investigators
Dec 6, 2006·The American Journal of Medicine·Russell D HullUNKNOWN LITE Trial Investigators
Apr 6, 2007·British Journal of Haematology·Anita HillPeter Hillmen
Apr 17, 2007·Seminars in Hematology·Alex Gatt, Michael Makris
Aug 1, 2007·Journal of Thrombosis and Haemostasis : JTH·H R BullerP W Kamphuisen
May 24, 2008·The Annals of Thoracic Surgery·Bruce D Spiess
Dec 17, 2008·Current Opinion in Rheumatology·Gunnar TomassonPeter A Merkel
Feb 19, 2009·British Journal of Haematology·Paolo Prandoni, Susan R Kahn
Mar 12, 2009·Thrombosis and Haemostasis·Eva K RomboutsFelix J M van der Meer
Jun 25, 2009·Current Opinion in Hematology·Sarah Ingber, William H Geerts
Jul 10, 2009·Blood·Bill Giannakopoulos, Steven A Krilis
Sep 10, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Agnes Y Y Lee

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Citations

Oct 12, 2013·Clinical Medicine : Journal of the Royal College of Physicians of London·Jecko Thachil
Jan 19, 2016·Journal of Thrombosis and Thrombolysis·Daniel M WittJack E Ansell
Oct 11, 2014·British Journal of Haematology·Matthew J LawrencePhillip A Evans

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