Recursive partitioning-based preoperative risk stratification for atrial fibrillation after coronary artery bypass surgery

American Heart Journal
Artyom SedrakyanHarlan M Krumholz

Abstract

Knowledge of the risk of atrial fibrillation (AF) for patients undergoing coronary artery bypass graft surgery (CABG) can guide decisions about prophylactic therapy. Accordingly, we sought to use tree-based methods to stratify patients into groups that will have similar risk of AF after CABG and informed decision making regarding aggressive prophylaxis of AF. We studied 1209 consecutive patients with isolated CABG performed in 1998-1999 at Yale-New Haven Hospital. Patients with preoperative AF were excluded. Tree-based analysis was carried out to stratify patients into similar groups regarding the risk of AF. Relative risks (RRs) and 95% CIs were calculated at each level of stratification. Age was the most important variable. The importance of other risk factors seemed to be different for younger and older patients. Although in the younger age group (< or =60 years) severity of coronary artery disease (RR 2.19, 95% CI 1.12-3.34) followed by hypertension (RR 1.82, 95% CI 1.23-2.68) were important predictors, in the older age subgroups (61-69 and > or =70 years), nothing or only ejection fraction <40% (RR 1.31, 95% CI 1.08-1.59) was important. In the highest-risk group, AF occurrence was 55% and, in the lowest-risk group, it was ...Continue Reading

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Citations

Sep 13, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Yuelin Li, Carolyn E Schwartz
Nov 15, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Carolyn E SchwartzTimothy Vollmer
Apr 11, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Carolyn E SchwartzMirjam A G Sprangers
Dec 21, 2010·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Marijana TadicNevenka Zivkovic
Jun 16, 2009·Journal of Cardiothoracic and Vascular Anesthesia·Jacek B CywinskiColleen Gorman Koch
Jan 21, 2010·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Mark W ParsonsUNKNOWN Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators
Nov 6, 2018·BMC Medical Research Methodology·Shi YanLian Leng Low

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