Red and processed meat intake and risk of colorectal adenomas: a meta-analysis of observational studies

International Journal of Cancer. Journal International Du Cancer
Xiaodong XuChuangang Fu

Abstract

Inconsistent results regarding the association between red and processed meat intake and the risk of colorectal adenoma (CRA), the precursor of colorectal cancer (CRC), have been reported. To provide a quantitative assessment of this association, we summarized the evidence from observational studies. Relevant studies were identified in MEDLINE and EMBASE until December 31, 2011. Summary relative risks (SRRs) with 95% confidence intervals (CIs) were pooled with a random-effects model. Between-study heterogeneity was assessed using the Cochran's Q and I(2) statistics. A total of 21 studies (16 case-control studies and five cohort/nested case-control studies) were included in this meta-analysis. The SRRs of CRA were 1.36 (95% CI = 1.17-1.58) for every 100 g/day increase in red meat intake, and 1.24 (95% CI = 1.12-1.36) for the highest versus the lowest level of red meat intake. Nonlinear dose-response meta-analysis indicated that CRA risk increased approximately linearly with increasing intake of red meat up to ~ 90 g/day, where the curve reached its plateau. Subgrouped analyses revealed that the increased risk of CRA with intake of red meat was independent of geographic locations, design and confounders. The SRRs of CRA was 1.28 ...Continue Reading

References

Jan 15, 1992·Journal of the National Cancer Institute·E GiovannucciW C Willett
Jun 1, 1992·American Journal of Epidemiology·S Greenland, M P Longnecker
Jun 1, 1990·Cell·E R Fearon, B Vogelstein
Sep 1, 1986·Controlled Clinical Trials·R DerSimonian, N Laird
Jul 1, 1993·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·G SteineckE Overvik
Jun 2, 1993·Journal of the National Cancer Institute·R S SandlerL L Kupper
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Aug 23, 2000·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·H YoonD Tomé
Mar 29, 2001·Digestive Diseases and Sciences·B Breuer-KatschinskiUNKNOWN Colorectal Adenoma Study Group
Feb 22, 2002·International Journal of Cancer. Journal International Du Cancer·Teresa NoratElio Riboli
Nov 21, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D W VoskuilP van 't Veer
Dec 11, 2003·JAMA : the Journal of the American Medical Association·David A LiebermanUNKNOWN VA Cooperative Study Group 380
Sep 24, 2004·International Journal of Cancer. Journal International Du Cancer·Brenda DiergaardeEllen Kampman
Aug 17, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Rashmi SinhaNathaniel Rothman
Sep 6, 2005·Cancer Research·Rashmi SinhaRichard B Hayes
Feb 16, 2006·International Journal of Cancer. Journal International Du Cancer·Petra A WarkEllen Kampman
Mar 4, 2006·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Jun 16, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kana WuRashmi Sinha
Sep 23, 2006·International Journal of Cancer. Journal International Du Cancer·Susanna C Larsson, Alicja Wolk
Feb 14, 2007·Cancer Detection and Prevention·Joanna Kruk
Feb 5, 2008·Gastroenterology·Edoardo BotteriAlbert B Lowenfels
Mar 4, 2008·Fertility and Sterility·Jaime MendiolaRafael Bernabeu
Mar 6, 2009·The American Journal of Clinical Nutrition·Dominik D AlexanderMark A Roberts
Mar 6, 2009·The American Journal of Clinical Nutrition·Sabine RohrmannJakob Linseisen
Apr 8, 2009·International Journal of Cancer. Journal International Du Cancer·Rachel R HuxleyMark Woodward
Apr 16, 2009·The American Journal of Gastroenterology·Leah M FerrucciAmanda J Cross
Apr 9, 2010·Pharmacogenetics and Genomics·Emma L NorthwoodGillian Smith
May 5, 2011·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Dominik D AlexanderKimberly A Lowe
Dec 15, 2011·British Journal of Cancer·L M FerrucciA J Cross

❮ Previous
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Citations

Apr 1, 2014·Journal of Cancer Research and Clinical Oncology·Peng SongQinghong Zhao
Jan 15, 2015·International Journal of Cancer. Journal International Du Cancer·Prudence R CarrMichael Hoffmeister
Mar 18, 2016·American Journal of Public Health·Joan SabatéSamuel Soret
Mar 7, 2014·International Journal of Cancer. Journal International Du Cancer·Lukas Schwingshackl, Georg Hoffmann
Jun 20, 2014·Alimentary Pharmacology & Therapeutics·J-Z ZhuY-M Li
Mar 26, 2016·Current Nutrition Reports·Lukas Schwingshackl, Georg Hoffmann
Nov 26, 2015·Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences·Parvane SaneeiAhmad Esmaillzadeh
Mar 5, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Cuili YangDejia Li
Jan 13, 2015·Gastroenterology·Mingyang SongAndrew T Chan
Dec 11, 2014·Digestive Diseases and Sciences·Ethan Bortniker, Joseph C Anderson
Oct 30, 2014·European Journal of Clinical Nutrition·Z H WangB Zhang
Apr 30, 2016·Critical Reviews in Food Science and Nutrition·Cem EkmekciogluHans-Peter Hutter
Sep 30, 2016·Cancer Epidemiology·Monica S Sierra, David Forman
May 30, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Cari M KitaharaWen-Yi Huang
Aug 3, 2016·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Luca GiraldiEmanuele Leoncini
May 23, 2014·The American Journal of Clinical Nutrition·Zaynah AbidRashmi Sinha
Aug 10, 2017·European Journal of Clinical Nutrition·C S C YipR Fielding
Sep 5, 2019·Cancer Science·Zobida IslamUNKNOWN Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
Dec 18, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·John D Potter
Mar 1, 2017·Comprehensive Reviews in Food Science and Food Safety·Thomas Van HeckeStefaan De Smet
May 1, 2018·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Lukas NiederreiterHerbert Tilg
Aug 10, 2021·Archives of Environmental & Occupational Health·Nader Rahimi KakavandiMohammad Abdollahi

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