Abstract
Red cell distribution width (RDW) has been shown to be associated with cardiovascular diseases (CVD). The relationship between RDW and carotid intima-media thickness (C-IMT), a marker of subclinical atherosclerosis, has been inconsistent in subjects with cardiovascular risk factors. In this study, we investigated the relationship between RDW and carotid atherosclerosis in people with type 2 diabetes. Four hundred sixty-nine people with type 2 diabetes without history of cardiovascular or cerebrovascular diseases were enrolled. Anthropometric measures and various biochemical parameters including RDW were assessed. Ultrasonographic measurement of carotid intima-media thickness was used to evaluate subclinical atherosclerosis. The participants were stratified into 3 groups according to RDW. The C-IMT increased gradually according to RDW tertiles (lowest, second, highest RDW tertiles; 0.740 ± 0.120, 0.772 ± 0.138, and 0.795 ± 0.139, respectively; p < 0.01). Multiple regression analysis and multivariate logistic regression analysis revealed that RDW was associated with C-IMT in people with type 2 diabetes, and it remained significant after control for various cardiovascular risk factors including body mass index, blood pressure, ins...Continue Reading
References
Dec 1, 1986·Circulation·P PignoliR Paoletti
Dec 1, 1996·Journal of Clinical Epidemiology·R JacksonW Kalsbeek
Feb 21, 1998·Annals of Internal Medicine·H N HodisS P Azen
Jan 8, 1999·The New England Journal of Medicine·D H O'LearyS K Wolfson
Jan 14, 1999·The New England Journal of Medicine·R Ross
Oct 14, 2000·American Journal of Epidemiology·R Din-DziethamH A Tyroler
Nov 1, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Fausta MichelettaLuigi Iuliano
Jun 19, 2004·Blood·Jeffrey S FriedmanSteven J Burakoff
Apr 27, 2005·Circulation·Martin SchillingerErich Minar
Jul 3, 2007·Journal of the American College of Cardiology·G Michael FelkerUNKNOWN CHARM Investigators
Jan 4, 2008·Circulation·Marcello TonelliUNKNOWN for the Cholesterol and Recurrent Events (CARE) Trial Investigators
Feb 7, 2008·Diabetes/metabolism Research and Reviews·Dario PitoccoGiovanni Ghirlanda
Nov 5, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S K KimY W Cho
Mar 11, 2009·Archives of Internal Medicine·Kushang V PatelJack M Guralnik
Mar 25, 2009·Archives of Internal Medicine·Todd S PerlsteinJoshua A Beckman
Mar 26, 2010·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Richard D SembaLinda P Fried
Oct 18, 2011·Diabetologia·N MalandrinoR J Smith
Nov 8, 2011·Journal of Diabetes and Its Complications·Shilpa B AsegaonkarRote Ajay
Dec 3, 2011·Coronary Artery Disease·Turgay IsikCharles Michael Gibson
Feb 28, 2013·Croatian Medical Journal·Mario SičajaVelimir Božikov
May 31, 2013·Clinical Hemorheology and Microcirculation·Maria FornalTomasz Grodzicki
May 21, 2014·Journal of Diabetes Investigation·Naoto KatakamiIichiro Shimomura
Jul 24, 2014·JACC. Cardiovascular Imaging·Tasneem Z Naqvi, Ming-Sum Lee
May 8, 2015·PloS One·Martin SöderholmGunnar Engström
May 11, 2015·Archives of Gerontology and Geriatrics·He JiaChunfang Xia
Oct 17, 2015·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Ariel FurerYaron Arbel
Citations
Jun 18, 2020·Tissue Engineering. Part a·Chenghao ZhangLachlan J Smith
Oct 31, 2019·Acta Medica (Hradec Králové)·Cengiz KadiyoranMehmet Akif Ozturk
Dec 13, 2019·Journal of Diabetes Research·Marwan Al-NimerTaha Mahwi
Mar 14, 2020·Scientific Reports·Linpei JiaHongliang Zhang
Jan 9, 2021·BMC Endocrine Disorders·Deyuan ZhangXing Zhong