PMID: 8614772Jan 1, 1996Paper

Red cell Na+/H+ exchange and B cell alloantigen 883 (D8/17) in patients with acute rheumatic fever and inactive rheumatic heart disease

Scandinavian Journal of Rheumatology
W KorenN Shostak

Abstract

The association of Na+/H+ antiport with 883 alloantigen was studied in patients with rheumatic disease. Simultaneous measurements were made of red cell Na+/H+ exchange and 883 alloantigen in microlymphocytotoxic test with D8/17 monoclonal antibodies in 20 patients with acute rheumatic fever, 20 patients with inactive rheumatic heart disease, 20 patients with atherosclerotic heart disease (stable anginal syndrome), and 20 healthy subjects. The number of 883(+) B cells and the Na+/H+ antiport activity were increased in rheumatic fever compared to healthy controls: 24.8 +/- 0.4 vs. 11.1 +/- 1.0% cells, 431 +/- 43 vs 121 +/- 12 micromol H+/l cells in min, respectively; p < 0.001; and in patients with rheumatic heart disease compared to patients with atherosclerotic heart disease; 25.7 +/- 1.8 vs. 9.8 +/- 1.1% cells, 482 +/- 73 vs. 124 +/- 12 micromol H+/l cells in min, respectively; p < 0.001.

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Citations

May 29, 2000·Pathophysiology : the Official Journal of the International Society for Pathophysiology·J Ahlqvist
May 5, 2005·Journal of Biomechanical Engineering·Daniel R EinsteinRichard P Cochran
Feb 1, 2007·Proceedings of the National Academy of Sciences of the United States of America·S A SissonMark M Tanaka
Dec 12, 2012·International Journal of Epidemiology·Sheena G Sullivan, Sander Greenland
Feb 7, 2012·American Journal of Epidemiology·Stephen R ColeDavid B Richardson
Oct 18, 2008·Biostatistics·Alexandros GryparisBrent A Coull
Jul 16, 2010·Bioinformatics·Timo ErkkiläHarri Lähdesmäki
Feb 23, 2012·Bioinformatics·J VanlierN A W van Riel
Mar 1, 2012·Bioinformatics·J VanlierN A W van Riel
Feb 11, 2009·Circulation·Penelope A BryantNigel Curtis

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