Red-shifted backbone N-H photocaging agents.

Organic & Biomolecular Chemistry
Alicia E Mangubat-MedinaZachary T Ball

Abstract

Light is a uniquely powerful tool for spatiotemporal control of molecular structure, necessitating the development of new photocaging approaches. This communication describes the design, synthesis, and reactivity of two new photoreactive boronic acid reagents for backbone N-H modification and subsequent photocleavage.

References

Mar 29, 2003·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Rajeshwar P Sinha, Donat P Häder
Nov 4, 2004·Journal of the American Chemical Society·Ning WuPeter G Schultz
Sep 30, 2006·Angewandte Chemie·Ulrike KusebauchChristian Renner
Apr 12, 2007·Biochemistry·Vishakha R ShembekarGeorge P Hess
Nov 4, 2009·Bioorganic & Medicinal Chemistry·L Nathan TumeyDiane H Boschelli
Nov 13, 2013·Chemistry : a European Journal·Ludovic FournierLudovic Jullien
Jun 5, 2015·The Journal of Organic Chemistry·Niranjan PandaDinesh Kumar Nayak
Jun 2, 2016·Journal of the American Chemical Society·Jun OhataZachary T Ball
Feb 9, 2018·Angewandte Chemie·Jun OhataZachary T Ball
Mar 3, 2018·The Journal of Physical Chemistry Letters·Christopher A HammerJosef Wachtveitl
May 8, 2018·Chemical Science·Yvonne BeckerAlexander Heckel
Jun 21, 2018·Journal of the American Chemical Society·Alicia E Mangubat-MedinaZachary T Ball

❮ Previous
Next ❯

Citations

Dec 23, 2020·Organic & Biomolecular Chemistry·Matthew D HammersMark D Distefano
Jul 29, 2021·Chemical Society Reviews·Alicia E Mangubat-Medina, Zachary T Ball
Oct 31, 2020·Chemical Reviews·Roy WeinstainPetr Klán

❮ Previous
Next ❯

Methods Mentioned

BETA
NMR

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.