Redox-active ferrocene-modified Cowpea mosaic virus nanoparticles.

Dalton Transactions : an International Journal of Inorganic Chemistry
Alaa A A AljabaliDavid J Evans

Abstract

A naturally occurring nanoparticle, the plant virus Cowpea mosaic virus, can be decorated with ferrocene derivatives, of various linker lengths with amine and carboxylate groups, on the external surface using a range of conjugation strategies. The multiple, organometallic, redox-active ferrocene moieties on the outer surface of the virus are electrochemically independent with reduction potentials that span a potential window of 0.16 V that are dependent on the site of modification and the nature of the ferrocene derivative. The number of ferrocenes coupled to each virus ranges from about 100 to 240 depending upon the conjugation site and the linker length and these redox active units can provide multielectron reservoirs.

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Citations

Jul 26, 2012·Molecular Pharmaceutics·Alaa A A AljabaliDavid J Evans
Apr 11, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Samuel EyleyWim Thielemans
Aug 7, 2012·Nanoscale·Alaa A A AljabaliDavid J Evans
Dec 15, 2015·Nature Communications·Emma L HeskethNeil A Ranson
Dec 10, 2015·Frontiers in Plant Science·Elisa TinazziLinda Avesani
Nov 6, 2012·Biomacromolecules·Amy M WenNicole F Steinmetz
Jan 22, 2019·Nanoscale·Alberto BerardiGeorge P Lomonossoff
Jul 19, 2012·Advanced Materials·Avinash J PatilStephen Mann
Sep 14, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yu ZhangFei Wang
Dec 13, 2017·Nanoscale·Alberto BerardiGeorge P Lomonossoff
Oct 9, 2020·Current Medical Imaging·Alaa A A AljabaliMurtaza M Tambuwala

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