Redox control in the pathophysiology of influenza virus infection.

BMC Microbiology
Ker-Kong ChenKazunari K Yokoyama

Abstract

Triggered in response to external and internal ligands in cells and animals, redox homeostasis is transmitted via signal molecules involved in defense redox mechanisms through networks of cell proliferation, differentiation, intracellular detoxification, bacterial infection, and immune reactions. Cellular oxidation is not necessarily harmful per se, but its effects depend on the balance between the peroxidation and antioxidation cascades, which can vary according to the stimulus and serve to maintain oxygen homeostasis. The reactive oxygen species (ROS) that are generated during influenza virus (IV) infection have critical effects on both the virus and host cells. In this review, we outline the link between viral infection and redox control using IV infection as an example. We discuss the current state of knowledge on the molecular relationship between cellular oxidation mediated by ROS accumulation and the diversity of IV infection. We also summarize the potential anti-IV agents available currently that act by targeting redox biology/pathophysiology.

References

Jan 1, 1992·Free Radical Research Communications·G D BuffintonR Stocker
May 1, 1990·Chemical & Pharmaceutical Bulletin·T NagaiH Yamada
Aug 30, 1989·Biochemical and Biophysical Research Communications·T NagaiH Yamada
Jun 1, 1994·Free Radical Biology & Medicine·D B Jacoby, A M Choi
Dec 1, 1995·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J V Formica, W Regelson
Nov 7, 1998·Antiviral Research·D MiyamotoY Suzuki
Mar 17, 2000·Circulation Research·K K GriendlingM Ushio-Fukai
Feb 13, 2001·The Journal of Clinical Investigation·J HiscottP Génin
Aug 25, 2001·The British Journal of Nutrition·R van den BergA Bast
Feb 8, 2002·Comparative Immunology, Microbiology and Infectious Diseases·M MilevaS Ribarov
Jan 11, 2003·Proceedings of the National Academy of Sciences of the United States of America·Takaaki AkaikeHiroshi Maeda
Feb 21, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Lucia NencioniAnna T Palamara
Mar 5, 2003·Trends in Molecular Medicine·Stephan LudwigThorsten Wolff
Mar 26, 2003·Free Radical Biology & Medicine·Jiyang CaiDean P Jones
Aug 5, 2003·BioFactors·Martine Torres, Henry Jay Forman
Sep 17, 2003·International Journal of Experimental Pathology·Pankaj KumarHanumantharao Guru Raj
Nov 1, 2003·Biochemical and Biophysical Research Communications·Tomohiro SawaHiroshi Maeda
Mar 6, 2004·International Journal of Immunopathology and Pharmacology·P Ghezzi, D Ungheri
Mar 31, 2004·Molecular Aspects of Medicine·Enrique Cadenas
Sep 15, 2004·Toxicology and Applied Pharmacology·Richard C ZangarSeema Verma
Apr 20, 2005·The Journal of Infectious Diseases·Anna T PalamaraEnrico Garaci
Aug 23, 2005·The Journal of Nutritional Biochemistry·Roberta MasellaClaudio Giovannini
Sep 3, 2005·Antiviral Research·Jae-Min SongBaik-Lin Seong
Jan 18, 2006·Cell Death and Differentiation·T Kawai, S Akira
Apr 21, 2006·Medical Hypotheses·Howard Friel, Harvey Lederman
Jun 22, 2006·Current Medicinal Chemistry·A FraternaleM Magnani
Jun 30, 2006·Trends in Immunology·Emma M Creagh, Luke A J O'Neill
Sep 22, 2006·Antioxidants & Redox Signaling·Nick R Leslie
Sep 22, 2006·Antioxidants & Redox Signaling·James A McCubreyRichard A Franklin
Jan 24, 2007·Physiological Reviews·Karen Bedard, Karl-Heinz Krause
Feb 28, 2007·The Journal of General Virology·Yeun-Kyung ShinYan Zhou
Apr 20, 2007·Journal of Leukocyte Biology·Mohamed LamkanfiGabriel Núñez
May 17, 2007·IUBMB Life·Sayuri MiyamotoPaolo Di Mascio
Jun 21, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Haley Neff-LaFordB Paige Lawrence

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Citations

Jan 7, 2021·Free Radical Research·Hung-Chi YangDaniel Tsun-Yee Chiu
Dec 10, 2020·Clinical and Translational Allergy·Jean BousquetUNKNOWN ARIA group
Oct 18, 2020·European Journal of Pharmacology·Revathy NadhanPriya Srinivas
Jun 20, 2021·Redox Biology·Desirée BartoliniFrancesco Galli
Nov 4, 2021·Biomedit︠s︡inskai︠a︡ khimii︠a︡·V V SalminA B Salmina

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Methods Mentioned

BETA
bronchoalveolar lavage

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