Redox enzymes immobilized on electrodes with solution cosubstrates. General procedure for simulation of time-resolved catalytic responses

Analytical Chemistry
Claude P AndrieuxJean-Michel Savéant

Abstract

In view of the existing and potential applications of electrochemical enzymatic catalysis with redox enzymes immobilized on the electrode surface in biosensors, a numerical calculation procedure for simulating their cyclic voltammetric responses is presented. It is applicable to systems involving a redox cosubstrate in solution. The cosubstrates, substrates, products, and inhibitors are assumed to diffuse linearly (planar electrode) between the electrode and the solution. The reactions in which the various forms of the immobilized enzyme participate may be as numerous and intricate as required by the simulation with no other restriction than the computing time. They may, at will, follow or not follow Michaelis-Menten kinetics. Slow charge-transfer cosubstrates are treated in the framework of Butler-Volmer kinetic law.

References

Apr 4, 1987·Lancet·D R MatthewsD Scott
Jan 1, 1997·Biosensors & Bioelectronics·J Rishpon, D Ivnitski
Jan 12, 1999·Diabetes Research and Clinical Practice·H S ChenL T Ho
Dec 26, 2001·Chemical Reviews·G S Wilson, Y Hu
Jan 5, 2002·Diabetes Technology & Therapeutics·G McGarraughR Weinstein
Jan 10, 2002·Journal of the American Chemical Society·Murielle DequaireJean-Michel Savéant
Sep 11, 2002·Toxicon : Official Journal of the International Society on Toxinology·Mark P KreuzerGeorge G Guilbault
Sep 19, 2002·Analytical Chemistry·Murielle Dequaire, Adam Heller
Aug 17, 2004·Biosensors & Bioelectronics·Guido CarpiniMarco Mascini
Sep 17, 2004·Journal of the American Chemical Society·Benoît LimogesDounia Yazidi
Aug 16, 2005·Analytical Chemistry·Gilles MarchandFrédéric Ginot

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