Redox-Responsive Polymer with Self-Immolative Linkers for the Release of Payloads

Macromolecular Rapid Communications
Supitchaya IamsaardDaniel Crespy

Abstract

Previous couplings of corrosion inhibitors to redox-responsive polymers via covalent bonding suffer from several drawbacks. It is presented here novel redox-responsive polymer-corrosion inhibitor conjugates that contain self-immolative linkers in their side chains. Very fast redox-induced release of tryptamine, a drug and a corrosion inhibitor, is observed after applying a reductive trigger.

References

Apr 2, 2008·Journal of the American Chemical Society·Amit SagiDoron Shabat
Jul 29, 2010·Journal of the American Chemical Society·Aaron P Esser-KahnJeffrey S Moore
Aug 21, 2013·Journal of the American Chemical Society·Li-Ping LvDaniel Crespy
Oct 11, 2013·Advanced Materials·Ashokanand VimalanandanMichael Rohwerder
Sep 16, 2014·Journal of Controlled Release : Official Journal of the Controlled Release Society·Shixian LvXuesi Chen
May 27, 2015·Advanced Materials·The Hai TranMichael Rohwerder
Sep 24, 2015·ACS Applied Materials & Interfaces·Zhaoliang ZhengDmitry Shchukin

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Citations

Nov 21, 2018·Chemical Communications : Chem Comm·Farzad SeidiDaniel Crespy
Sep 22, 2020·Chemical Communications : Chem Comm·Farzad Seidi, Daniel Crespy
Feb 18, 2021·ACS Applied Materials & Interfaces·Miguel Gisbert-GarzaránMaría Vallet-Regí

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