Redox-responsive vesicles prepared from supramolecular cyclodextrin amphiphiles

Carbohydrate Research
Huacheng ZhangLizhen Sun

Abstract

Redox-responsive vesicles self-assembled by supramolecular cyclodextrin amphiphiles, consisting of the guest (N-1-decyl-ferrocenylmethylamine, 1) and the host (2-O-carboxymethyl-beta-cyclodextrin, CM-beta-CD), were prepared. The morphologies and sizes of these novel vesicles in an aqueous solution were observed by transmission electron microscopy (TEM) and were confirmed by atomic force microscopy (AFM) and dynamic light scattering (DLS) measurements. The effects of the host-guest ratio, the concentration and the solvent composition of water and methanol on vesicles were investigated in detail. The interactions between the host and the guest, the complex stoichiometry, the stability constant and conformations of 1.CM-beta-CD in aqueous solution were investigated by cyclic voltammetry (CV), UV and nuclear magnetic resonance (NMR) measurements. According to the complex stoichiometry and 'tadpole-like' spatial conformations, the supramolecular cyclodextrin amphiphiles made from 1.CM-beta-CD were proposed to form the membranes of the vesicles. This kind of vesicle system was responsive to an oxidizing agent, which could pave the way to combine supramolecular host-guest chemistry and membrane chemistry for potentially functional app...Continue Reading

References

Oct 16, 1999·Journal of Controlled Release : Official Journal of the Controlled Release Society·D DuchêneG Ponchel
Mar 30, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Jianhong LiuKam C Tam
Jul 13, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Antonella CristianoBart Jan Ravoo
Aug 21, 2007·Micron : the International Research and Review Journal for Microscopy·Yifeng HeHongcheng Gao
Nov 17, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Jiong ZouMing Jiang
Jan 27, 2009·Chemical Society Reviews·Jens Voskuhl, Bart Jan Ravoo
Apr 22, 2009·The Journal of Physical Chemistry. B·C Cabaleiro-LagoJ Pérez-Juste

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Citations

Dec 10, 2013·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·N RajendiranJ Saravanan
Jan 1, 2010·Acta Crystallographica. Section E, Structure Reports Online·Li-Zhen SunAi-You Hao
Apr 15, 2016·Macromolecular Rapid Communications·Xiaojin ZhangRenxi Zhuo
May 7, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Nagaraj Nayak, Karical R Gopidas
Apr 30, 2019·ChemNanoMat : Chemistry of Nanomaterials for Energy, Biology and More·E J TownsendC F J Faul
Feb 17, 2021·Advances in Colloid and Interface Science·Larissa Dos Santos Silva AraújoLeonardo Chiappisi
May 23, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Tao SunGuangcun Liu
Dec 1, 2012·The Journal of Physical Chemistry. B·Tao SunAiyou Hao
Jun 26, 2013·Journal of the American Chemical Society·Qunpeng DuanLeyong Wang

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