PMID: 1212807May 1, 1975Paper

Reduced antibody-dependent cell-mediated cytotoxicity in systemic lupus erythematosus

Clinical and Experimental Immunology
J SchneiderF P Quismorio

Abstract

The peripheral blood mononuclear cells from twenty-three patients with SLE were studied. They showed a reduction in antibody-dependent cell-mediated cytotoxicity. This reduction was significantly related to disease activity. No correlations were found with other clinical features. Some of the possible explanations for this finding are discussed.

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