PMID: 2106775Mar 1, 1990Paper

Reduced arachidonate in serum phospholipids and cholesteryl esters associated with vegetarian diets in humans

The American Journal of Clinical Nutrition
S D PhinneyR T Holman

Abstract

Lipid fractions such as phospholipids (PLs), cholesteryl esters (CEs), and free fatty acids (FFAs) represent source pools for eicosanoid synthesis. To determine whether dietary habits affect the enrichment of 20:4n-6 in these precursor pools, we studied humans with partial or complete arachidonate restriction resulting from chronic avoidance of animal fat and tissue. Fasting serum was obtained from omnivorous control subjects (Omni, n = 100), semivegetarians (Semiveg, n = 16), and vegetarians (Veg, n = 25). PLs, CEs, FFAs, and triglyceride (TG) fatty acids were quantitated by thin-layer and gas chromatography. Serum 20:4n-6 was lower in the PL fraction in both Veg (p less than 0.01) and Semiveg groups (p less than 0.05) than in the Omni group and lower in the CE fraction in the Veg group (p less than 0.05). Serum 18:2n-6 did not differ between groups for any serum lipid fraction. 18:3n-3 was elevated in PLs and CEs of both Veg (p less than 0.05 and 0.01) and Semiveg groups (p less than 0.05 and 0.01) compared with the Omni group but did not result in differences in 20:5n-3 in PLs or CEs between diet groups. The lower concentration of 20:4n-6 in serum PLs and CEs of the Veg group indicates that dietary arachidonic acid enriches ...Continue Reading

Citations

May 8, 1999·The American Journal of Clinical Nutrition·D LiA Turner
Jun 9, 2001·The Prostate·L M NewcomerJ L Stanford
Jul 18, 2006·The American Journal of Clinical Nutrition·Linda M ArterburnHarry Oken
Jul 30, 2010·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Yangyan ZhouZhi-Jie Liu
Jan 1, 1994·Lipids·R T HolmanJ W Crofts
Aug 17, 1999·Medicine and Science in Sports and Exercise·G A Gaesser
Sep 9, 1999·The American Journal of Clinical Nutrition·J Kjeldsen-Kragh
Jun 11, 2004·Annual Review of Nutrition·Manabu T Nakamura, Takayuki Y Nara
Feb 29, 2008·Annals of Nutrition & Metabolism·Margit KornsteinerIbrahim Elmadfa
Jan 1, 1995·Journal of Inherited Metabolic Disease·M GiovanniniE Riva
Jul 1, 1996·European Journal of Pediatrics·M GiovanniniE Riva
Mar 1, 1996·Lipids·S D Phinney
Oct 21, 2014·Journal of Food Science and Technology·Narinder KaurAnil K Gupta
Jan 1, 1993·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·C C ChangM E Gershwin
Aug 18, 2004·Journal of the American College of Nutrition·Paola BenattiMenotti Calvani
Jun 6, 2003·Lipids·Julia ArayaVanessa García
Mar 30, 2002·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·C Leigh BroadhurstWalter F Schmidt
Jan 20, 1998·Nutrition·C Galli, F Marangoni
Nov 25, 2000·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M R FokkemaF A Muskiet
Jan 1, 1992·Progress in Lipid Research·D F Horrobin
Jan 1, 1993·Prostaglandins, Leukotrienes, and Essential Fatty Acids·C GalliG Galella

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