Reduced autonomic activity during stepwise exposure to high altitude

Acta Physiologica Scandinavica
K SevreM Rostrup

Abstract

Several studies have shown increased sympathetic activity during acute exposure to hypobaric hypoxia. In a recent field study we found reduced plasma catecholamines during the first days after a stepwise ascent to high altitude. In the present study 14 subjects were exposed to a simulated ascent in a hypobaric chamber to test the hypothesis of a temporary reduction in autonomic activity. The altitude was increased stepwise to 4500 m over 3 days. Heart rate variability (HRV) was assessed continuously in seven subjects. Baroreceptor reflex sensitivity (BRS) was determined in eight subjects with the 'Transfer Function' method at baseline, at 4500 m and after returning to baseline. Resting plasma catecholamines and cardiovascular- and plasma catecholamine- responses to cold pressor- (CPT) and mental stress-test (MST) were assessed daily in all and 12 subjects, respectively. Data are mean +/- SEM. Compared with baseline at 4500 m there were lower total power (TP) (35 457 +/- 26 302 vs. 15 001 +/- 11 176 ms2), low frequency (LF) power (3112 +/- 809 vs. 1741 +/- 604 ms2), high frequency (HF) power (1466 +/- 520 vs. 459 +/- 189 ms2) and HF normalized units (46 +/- 0.007 vs. 44 +/- 0.006%), P < or = 0.001. Baroreceptor reflex sensitivit...Continue Reading

References

Apr 1, 1992·Circulation·J J McMurrayJ J Morton
Jul 1, 1991·Journal of Applied Physiology·P BärtschO Oelz
Oct 1, 1990·Journal of Hypertension·M G ZieglerH Elayan
Aug 1, 1990·Clinical Cardiology·M Malik, A J Camm
Nov 1, 1988·Journal of Applied Physiology·J P RichaletF Lhoste
Aug 1, 1987·International Journal of Sports Medicine·P BouissouP Pesquies
Jan 1, 1968·Pflügers Archiv : European journal of physiology·E J Becker, F Kreuzer
Jul 1, 1966·Science·E G McGeer, P L McGeer
Sep 1, 1984·Acta Physiologica Scandinavica·I OsP Leren
Apr 1, 1995·Proceedings of the Society for Experimental Biology and Medicine·W Henley, L Bellush
Mar 1, 1994·Journal of Applied Physiology·A M AntezanaJ P Richalet
Jan 1, 1994·British Heart Journal·M Malik, A J Camm
Jan 1, 1996·Clinical Science·M T La Rovere
Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·R PeriniA Veicsteinas
Feb 1, 1997·Clinical Cardiology·J Kautzner, A J Camm
Dec 31, 1997·Circulation·D L Eckberg
May 13, 1998·Acta Physiologica Scandinavica·M Rostrup
May 1, 1964·Medicine·J B STANBURY, V HUGHES
Mar 1, 1992·Trends in Cardiovascular Medicine·J M WhartonH C Strauss

❮ Previous
Next ❯

Citations

Jul 25, 2009·European Journal of Applied Physiology·Petra ZupetZarko Finderle
Feb 13, 2013·European Journal of Applied Physiology·S J BrownT Mündel
May 24, 2007·Amino Acids·M RostrupJ Haavik
Feb 1, 2007·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Roger HainsworthMaria Rivera-Chira
Nov 22, 2007·Sleep & Breathing = Schlaf & Atmung·M BurtscherH Gatterer
Sep 14, 2004·Journal of Hypertension·Henrik M ReimsSverre E Kjeldsen
Jan 7, 2010·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Hsien-Hao HuangChen-Hsen Lee
Aug 5, 2004·Medicine and Science in Sports and Exercise·Paola PavanAngelo Avogaro
Jun 27, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Nadine Messerli-BurgyKurt Laederach-Hofmann
Dec 22, 2009·Sports Medicine·Gregoire P MilletJ P Richalet
Feb 13, 2008·Journal of Cardiovascular Medicine·Efstratios K TheofilogiannakosGeorge Anogianakis
Oct 17, 2003·High Altitude Medicine & Biology·Jack A LoeppkyRobert C Roach
Sep 28, 2005·High Altitude Medicine & Biology·Camilo PoveaJean-Pierre Fouillot
Jan 16, 2016·Clinical Physiology and Functional Imaging·Christopher John BoosAdrian Mellor
Jun 29, 2007·Respiratory Physiology & Neurobiology·Roger Hainsworth, Mark J Drinkhill
Mar 17, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jacques PirenneBenoit Pirotte
Apr 28, 2005·Neuroscience Letters·Cong Chi Denis TranCharles-Yannick Guézennec
May 22, 2013·TheScientificWorldJournal·Turhan SanBurak Cakir
Jun 20, 2015·Australasian Physical & Engineering Sciences in Medicine·Da ZhangMengsun Yu
Jun 5, 2015·Sleep & Breathing = Schlaf & Atmung·Giuseppe InsalacoSalvatore Romano
Sep 4, 2014·Acta Physiologica Hungarica·Stephen J BrownT Mündel
Jan 1, 2012·Journal of Central Nervous System Disease·William E ShellDavid S Silver
Apr 14, 2017·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Adrian MellorChristopher J Boos
Jan 6, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Qi FuBenjamin D Levine
Jul 10, 2010·American Journal of Physiology. Gastrointestinal and Liver Physiology·Søren MøllerFlemming Bendtsen
Dec 13, 2019·Journal of Applied Physiology·Marc M BergerPeter Bärtsch
May 16, 2020·High Altitude Medicine & Biology·Jesús Álvarez-HermsMartin Burtscher
Mar 3, 2017·European Journal of Applied Physiology·Ming Ling YihShi-Chuan Chang
May 18, 2004·Journal of Applied Physiology·Jérémy CornoloJean-Paul Richalet
Sep 26, 2020·Frontiers in Physiology·Mathias Roland AebiGrégoire P Millet
Dec 17, 2017·European Journal of Applied Physiology·Laurent SchmittGregoire P Millet

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Applied Physiology and Occupational Physiology
R PeriniA Veicsteinas
The American Journal of the Medical Sciences
Yi-Chu ChenShi-Chuan Chang
© 2022 Meta ULC. All rights reserved