Reduced bladder capacity in patients receiving intravesical chemoprophylaxis with mitomycin C

British Journal of Urology
A EijstenD Hauri

Abstract

After complete resection of superficial bladder carcinoma (Tis-2, G1-3), 75 patients were treated prophylactically with either 20 or 30 mg mitomycin C. Six patients developed a substantial reduction in bladder capacity (less than 200 ml). In 2 patients radical cystectomy of an otherwise tumour-free fibrotic bladder was necessary. The results of long-term treatment (2 years) suggest that reduced bladder capacity correlates with the cumulative dosage of mitomycin C.

Citations

Nov 1, 1993·British Journal of Urology·A R WassG H Urwin
Apr 2, 2013·The Urologic Clinics of North America·Joshua G Griffin, Jeff Holzbeierlein
May 16, 2006·The Journal of Urology·Madhusudan P KoyaMark S Soloway
May 10, 2005·The Journal of Urology·Dirk MichielsenJean-Jacques Wyndaele
Oct 29, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Renzo ColomboMichele Pavone-Macaluso
Jan 1, 1992·Journal of Cellular Biochemistry. Supplement·M S Soloway, P E Perito

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