PMID: 8611644Jan 17, 1996Paper

Reduced carnitine palmitoyl transferase activity and altered acyl-trafficking in red blood cells from hemodialysis patients

Biochimica Et Biophysica Acta
B de los ReyesJ Arenas

Abstract

We measured carnitine palmitoyl transferase activity, free carnitine, and long chain acyl carnitine levels in erythrocytes from 15 uremic patients and 25 controls. Carnitine palmitoyl transferase levels in patients were significantly lower than in controls. The levels of free carnitine and long chain acyl carnitines as well as the long chain acyl carnitine/free carnitine ratio were significantly higher in patients than in controls. Our results suggest that hemodialysis causes alteration in the acyl-trafficking in red blood cells membrane.

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Citations

Apr 2, 1999·Early Human Development·J ArenasY Campos
Dec 14, 2004·Annals of the New York Academy of Sciences·Menotti CalvaniEric P Brass
Jan 23, 2021·International Journal of Molecular Sciences·Travis NemkovAngelo D'Alessandro
May 1, 2021·Nutrients·Hiroyuki TakashimaMasanori Abe

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