Reduced cerebral oxygen saturation measured by absolute cerebral oximetry during thoracic surgery correlates with postoperative complications

British Journal of Anaesthesia
R KazanT M Hemmerling

Abstract

Regional cerebral oxygen saturation (S(ct)O(2)) has recently been shown to decrease significantly during thoracic surgery. The present study investigates whether these desaturations are related to postoperative complications. Fifty patients undergoing thoracic surgery with a single-lung ventilation (SLV) of >45 min duration were enrolled. Regional cerebral oxygen saturation was measured using absolute oximetry; standard clinical variables, and SOFA and Clavien scores were recorded. Correlation between minimum S(ct)O(2) during SLV and postoperative complication scores was analysed using Pearson's correlation test, chi(2) test, and logistic regression. Forty-seven patients underwent lobectomy, two patients a pneumonectomy and 1 patient a chest wall resection. Eighty-two per cent of the patients had a decrease in S(ct)O(2) of >15% from baseline value, and 10% of the patients had a minimal absolute S(ct)O(2) value between 45% and 55%. The minimal absolute S(ct)O(2) values during SLV correlated with the Clavien score (R(2)=0.098, P=0.0201) and the non-respiratory SOFA score (R(2)=0.090, P=0.0287). By defining a threshold of S(ct)O(2)=65%, the odds ratio of having a non-respiratory organ failure was 2.37 (95% CI 1.18-4.39, P=0.043) a...Continue Reading

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Citations

Apr 3, 2012·Journal of Clinical Monitoring and Computing·T W L ScheerenL A Schwarte
May 11, 2013·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Ryan BrinkmanW Alan C Mutch
Nov 18, 2010·British Journal of Anaesthesia·C Zaouter, E Arbeid
Mar 4, 2014·Annales Françaises D'anesthèsie Et De Rèanimation·L ValenciaR Y Santana
Aug 4, 2010·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Jesse M EhrenfeldAtul Gawande
Oct 17, 2015·Journal of Cardiothoracic and Vascular Anesthesia·Alexander J GregoryHilary P Grocott
Sep 22, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Ioanna ApostolidouNancy A Nussmeier
Mar 5, 2016·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·John M Murkin, Mauricio Giraldo
Nov 4, 2015·Anaesthesia Critical Care & Pain Medicine·Lucía ValenciaOto Padrón
Dec 18, 2014·Journal of Clinical Monitoring and Computing·N MurphyN Conlon
May 6, 2016·Der Anaesthesist·T KammererV von Dossow
May 18, 2011·British Journal of Anaesthesia·A Ng, J Swanevelder
Feb 13, 2018·Seminars in Dialysis·Clare MacEwenChristopher Pugh
Sep 28, 2010·Anesthesia and Analgesia·Patrick J TigheS Parekattil
Mar 9, 2017·Journal of the American Society of Nephrology : JASN·Clare MacEwenLionel Tarassenko
Nov 23, 2013·Current Opinion in Anaesthesiology·Inderveer MahalHilary P Grocott
Nov 23, 2013·Current Opinion in Anaesthesiology·Roland Tomasi, Vera von Dossow-Hanfstingl
May 20, 2020·Journal of Clinical Monitoring and Computing·Ekaterina TsymbalNeal W Fleming
May 11, 2017·Journal of Clinical Monitoring and Computing·Hongyi LiPeng Wang
Nov 7, 2014·Journal of Neurosurgical Anesthesiology·Marco M GaravagliaGregory M T Hare
Oct 21, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Bryan E MarchantRoger L Royster
Jul 1, 2020·Thoracic Surgery Clinics·Melina Shoni, Gerardo Rodriguez
Jun 10, 2021·Türk göğüs kalp damar cerrahisi dergisi·Atakan ErkılınçMustafa Emre Gürcü
Aug 8, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Jafer AliHarish Ramakrishna

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