Abstract
Reduced exercise capacity is known to be an important predictor of poor prognosis and disability in patients with cardiovascular diseases and chronic heart failure, and even members of the general population. However, data about exercise capacity assessed by cardiopulmonary exercise testing (CPX) in acute myocardial infarction (AMI) patients who underwent primary percutaneous coronary intervention (PCI) is scarce. Among 594 consecutive AMI patients who underwent primary PCI, we examined 136 patients (85.3% men, 64.9 ± 11.9 years) who underwent CPX during hospitalization for AMI. CPX was usually performed 5 days after the onset of AMI. Reduced exercise capacity was defined as peak VO2 ≤ 12. Clinical outcomes including all-cause death, myocardial infarction, and hospitalization due to heart failure were followed. Among 136 patients, reduced exercise capacity (peak VO2 ≤ 12) was seen in 38 patients (28%). Patients with reduced exercise capacity were older, more likely to have hypertension, and had lower renal function. In echocardiography, patients with reduced exercise capacity had higher E/e' and larger left atrial dimension. Multivariate logistic analysis showed that E/e' (OR 1.19, 95% CI 1.09-1.31, p < 0.001) was an independen...Continue Reading
References
Mar 11, 1991·Circulation·D M ManciniJ R Wilson
Jun 1, 1986·Journal of Applied Physiology·W L BeaverB J Whipp
Jun 1, 1986·The American Journal of Cardiology·M B HigginbothamF R Cobb
Feb 1, 1994·Journal of the American College of Cardiology·L VanheesA Amery
Mar 15, 2002·The New England Journal of Medicine·Jonathan MyersJ Edwin Atwood
Jun 1, 2002·Journal of the American College of Cardiology·Tamara B HorwichJeff Borenstein
Aug 5, 2005·The New England Journal of Medicine·Martha GulatiRonald A Thisted
Jul 26, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Yusuke KasaharaTakashi Masuda
Aug 2, 2006·Circulation·Jacob E MøllerJae K Oh
Mar 4, 2008·Heart Failure Clinics·Dalane W Kitzman, Leanne Groban
May 14, 2008·Circulation·J E MøllerC M Yu
Jul 29, 2008·American Heart Journal·Steven J KeteyianPhilip A Ades
Feb 16, 2011·Circulation·Ross Arena, Kathy E Sietsema
Mar 19, 2013·Journal of the American College of Cardiology·Yasushi MatsuzawaKazuo Kimura
Nov 13, 2014·Circulation. Cardiovascular Quality and Outcomes·Deborah A LevineTheodore J Iwashyna
Feb 25, 2015·Clinical Cardiology·Ricardo Fontes-CarvalhoAdelino Leite-Moreira
Jan 19, 2016·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Mandeep R MehraUNKNOWN International Society for Heart Lung Transplantation (ISHLT) Heart Failure and Transplantation Council
Feb 20, 2016·Journal of the American College of Cardiology·Steven J KeteyianUNKNOWN HF-ACTION Investigators
Mar 21, 2016·American Heart Journal·Ali ShafiqSteven J Keteyian
Aug 10, 2016·Lancet·Grant W ReedChristopher P Cannon
May 26, 2017·The New England Journal of Medicine·Jeffrey L Anderson, David A Morrow
Mar 2, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Toru KondoToyoaki Murohara
Aug 31, 2018·European Heart Journal·Kristian ThygesenUNKNOWN ESC Scientific Document Group
Citations
Jan 23, 2021·Heart and Vessels·Hiroaki HiraiwaToyoaki Murohara
Jan 30, 2021·Heart and Vessels·Asami OguraYuichi Matsuda
Feb 7, 2021·Heart and Vessels·Megumi HoshiaiTakanori Yasu