Reduced fertility with impairment of early-stage embryos observed in mice lacking Lgr4 in epithelial tissues

Fertility and Sterility
Yasuaki MohriKatsuhiko Nishimori

Abstract

Lgr4 is one of the genes identified as novel G protein-coupled receptor genes designated Lgr4-Lgr8, with high homology with FSH receptor, LH receptor, and TSH receptor genes, but studies of Lgr4-mutant mice have suggested that Lgr4 has essential functions in development. This is the first report describing the relationship between the functions of Lgr4 and female reproductive systems.

References

Aug 1, 1995·Biology of Reproduction·Y SendaiY Araki
Jul 8, 1997·Proceedings of the National Academy of Sciences of the United States of America·M TarutaniJ Takeda
May 18, 2001·Endocrinology·J S Richards
Feb 9, 2002·The Journal of Endocrinology·K Hardy, S Spanos
Sep 25, 2003·In Vitro Cellular & Developmental Biology. Animal·Tomohiro UmezuYasuhiro Tomooka
Jul 20, 2005·Histochemistry and Cell Biology·Grégory Van SchooreGilbert Vassart
Sep 15, 2005·Journal of Cell Science·Julia VentRichard Hallworth
Jun 21, 2006·Nephron. Experimental Nephrology·Shigeki KatoKatsuhiko Nishimori
Aug 4, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·Phil G Knight, Claire Glister
Nov 3, 2006·Biology of Reproduction·Takayuki HoshiiKen-ichi Yamamura
Oct 30, 2007·The Journal of Biological Chemistry·Eiichi TakakiAkira Nakai
Apr 22, 2008·Proceedings of the National Academy of Sciences of the United States of America·Jinsheng WengMingyao Liu
Jul 25, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Yasuaki MohriKatsuhiko Nishimori
Nov 13, 2009·Biology of Reproduction·Hiromi YamanouchiYasuhiro Tomooka

❮ Previous
Next ❯

Citations

Jul 28, 2011·Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation·K OyamaK Nishimori
Jan 19, 2012·PloS One·Henriette PoatyAlain Bernheim
Jul 11, 2013·Journal of Ophthalmology·Stefan SiwkoMingyao Liu
Oct 27, 2012·Bulletin of Environmental Contamination and Toxicology·Jiachen ShiBing Shao
Apr 28, 2011·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Yasuaki MohriKatsuhiko Nishimori
Oct 30, 2014·Bioscience, Biotechnology, and Biochemistry·Tomoyo KidaKatsuhiko Nishimori
Sep 4, 2015·Biology of Reproduction·Masae KoizumiKatsuhiko Nishimori
Jun 29, 2012·Bioscience, Biotechnology, and Biochemistry·Yasuaki MohriKatsuhiko Nishimori
May 16, 2019·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Vanessa de OliveiraAndy V Babwah
Aug 27, 2013·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Mizuki SoneKatsuhiko Nishimori
Dec 23, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Zhiying YueMingyao Liu
May 30, 2013·Development·Nick BarkerHans Clevers
May 6, 2021·International Journal of Molecular Sciences·Alejandro Ordaz-RamosKarla Vazquez-Santillan
Feb 18, 2014·Genes & Development·Wim de LauHans Clevers

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation
Kazunori OyamaKatsuhiko Nishimori
Developmental Dynamics : an Official Publication of the American Association of Anatomists
Yasuaki MohriKatsuhiko Nishimori
Proceedings of the National Academy of Sciences of the United States of America
Jinsheng WengMingyao Liu
© 2021 Meta ULC. All rights reserved