Reduced global longitudinal and radial strain with normal left ventricular ejection fraction late after effective repair of aortic coarctation: a CMR feature tracking study.

The International Journal of Cardiovascular Imaging
Shelby KuttyPhilipp Beerbaum

Abstract

We sought to determine whether global and regional left ventricular (LV) strain parameters were altered in repaired coarctation of the aorta (COA) with normal LV ejection fraction (EF) when compared with healthy adult controls, and whether such alterations were related to LV hypertrophy (LVH). We identified 81 patients after COA repair (31 female, age 25 ± 8.5 years) with inclusion criteria at follow-up CMR of: age ≥13 years, time post-repair ≥10 years, no aortic valve disease, LV-EF >50%). LV deformation indices derived using CMR-feature tracking and volumetric EF were compared between COA patients and normal controls (n = 20, 10 female, age 37 ± 7 years), and between COA with versus without LVH. In repaired COA versus controls, LV-EF (%) was 62 ± 7.2 versus 58 ± 3.0 (p = 0.01), and LV mass (g/m(2)) 66 ± 16.8 versus 57.7 ± 6.0 (p = 0.0001). LV global longitudinal strain (GLS) was decreased to -17.0 ± 4.7% in COA (-20 ± 5% in controls, p = 0.02), and global radial strain (GRS) reduced to 40 ± 15% (50 ± 12.4% in controls, p = 0.003). The global circumferential strain (GCS) was preserved in COA at -23 ± 4.7% (-24.6 ± 2.4% in controls, p = 0.14). Regionally, LS decrease was marked in the basal segments (septal, p = 0.005, lateral,...Continue Reading

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Citations

Apr 2, 2014·The International Journal of Cardiovascular Imaging·Hiram G BezerraNico R L Van de Veire
Jan 19, 2016·The International Journal of Cardiovascular Imaging·Myrthe E MentingJolien W Roos-Hesselink
Oct 16, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Philipp HeermannAlexander C Bunck
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May 2, 2021·Current Heart Failure Reports·Torben Lange, Andreas Schuster

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Aortic coarctation is a congenital condition characterized by narrowing of the aorta. Discover the latest research on this disease here.