Reduced graphene oxide/PAMAM-silver nanoparticles nanocomposite modified electrode for direct electrochemistry of glucose oxidase and glucose sensing

Biosensors & Bioelectronics
Zhimin LuoLianhui Wang

Abstract

Reduced graphene oxide/PAMAM-silver nanoparticles nanocomposite (RGO-PAMAM-Ag) was synthesized by self-assembly of carboxyl-terminated PAMAM dendrimer (PAMAM-G3.5) on graphene oxide (GO) as growing template, and in-situ reduction of both AgNO(3) and GO under microwave irradiation. The RGO-PAMAM-Ag nanocomposite was used as a novel immobilization matrix for glucose oxidase (GOD) and exhibited excellent direct electron transfer properties for GOD with the rate constant (K(s)) of 8.59 s(-1). The fabricated glucose biosensor based on GOD electrode modified with RGO-PAMAM-Ag nanocomposite displayed satisfactory analytical performance including high sensitivity (75.72 μA mM(-1) cm(-2)), low detection limit (4.5 μM), an acceptable linear range from 0.032 mM to 1.89 mM, and also preventing the interference of some interfering species usually coexisting with glucose in human blood at the work potential of -0.25 V. These results indicated that RGO-PAMAM-Ag nanocomposite is a promising candidate material for high-performance glucose biosensors.

References

Oct 1, 1987·Analytical Chemistry·D E Reed, F M Hawkridge
Jan 13, 2004·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Tao LiuNaoki Matsuda
Sep 17, 2004·Journal of the American Chemical Society·J Justin GoodingD Brynn Hibbert
Nov 5, 2004·Chembiochem : a European Journal of Chemical Biology·Xin GanGenxi Li
Aug 4, 2005·Biosensors & Bioelectronics·Xiangling RenJun Jiao
Feb 1, 2007·Journal of the American Chemical Society·Gökçe Su PulcuSean J Elliott
Mar 3, 2007·Nature Materials·A K Geim, K S Novoselov
Apr 5, 2008·Biosensors & Bioelectronics·Xiaoqing LiuGuobao Xu
Jul 26, 2008·Nature Nanotechnology·Dan LiGordon G Wallace
Apr 4, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·J I ParedesJ M D Tascón
Jul 8, 2009·Small·Renu PasrichaAvanish Kumar Srivastava
Nov 4, 2009·Biosensors & Bioelectronics·Changsheng ShanLi Niu
Feb 27, 2010·Angewandte Chemie·Wenrong YangFilip Braet
Mar 31, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Yong LiuLiming Dai

❮ Previous
Next ❯

Citations

Oct 22, 2013·ACS Applied Materials & Interfaces·Nan GaoJiang Jiang
May 28, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Tie LiMingxin Ye
Aug 18, 2012·Expert Opinion on Drug Delivery·Priti P PednekarVilasrao J Kadam
Nov 17, 2015·IEEE Transactions on Nanobioscience·Feifei WangWen Li
Sep 28, 2016·IET Nanobiotechnology·Claramaría Rodríguez-GonzálezVíctor M Castaño
Nov 26, 2013·Materials Science & Engineering. C, Materials for Biological Applications·Selvakumar PalanisamyShen-Ming Chen
Oct 17, 2018·Physical Chemistry Chemical Physics : PCCP·Abhay N SinghPravin P Ingole
Mar 1, 2016·Beilstein Journal of Nanotechnology·Martina BanchelliGabriella Caminati
Mar 29, 2014·Physical Chemistry Chemical Physics : PCCP·Marccus V A MartinsFrank N Crespilho
Feb 14, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yue ZhangJian-Hua Wang
Mar 29, 2019·Bioelectrochemistry·Jeyaraman Shankara Narayanan, Gymama Slaughter
Aug 13, 2018·ACS Biomaterials Science & Engineering·Krishanu Ghosal, Kishor Sarkar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.