PMID: 2506536May 1, 1989Paper

Reduced growth hormone releasing factor (GHRF)-like immunoreactivity and GHRF gene expression in the hypothalamus of aged rats

Peptides
V DeGennaro ColonnaE E Müller

Abstract

Growth hormone releasing factor-like immunoreactivity (GHRF-LI) and GHRF mRNA levels were evaluated in the hypothalamus of aged (24 months) and young (3 months) rats by semiquantitative immunocytochemistry and slot blot hybridization technique, respectively. Simultaneous detection of reduced GHRF-LI and GHRF mRNA levels in aged rats as compared to young counterparts demonstrates the existence in aged rats of an impaired function of GHRF-producing neurons.

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Citations

Aug 1, 1993·Mechanisms of Ageing and Development·G M ConsoleR G Goya
Mar 1, 1991·Peptides·V De Gennaro ColonnaE E Müller
Jul 1, 1994·Neurochemistry International·V De Gennaro ColonnaE E Müller
Jul 1, 1990·Neurobiology of Aging·W E SonntagR M Booze
Jul 1, 1994·Neurobiology of Aging·L A Frohman
Jan 1, 1996·Neurobiology of Aging·I ShimokawaT Ikeda
Aug 1, 1992·Psychoneuroendocrinology·T F Sadow, R T Rubin
Aug 1, 1992·Psychoneuroendocrinology·A R HoffmanG P Ceda
Oct 17, 2002·Frontiers in Neuroendocrinology·J Peter H Burbach
Oct 24, 2002·Neurobiology of Aging·Eugenio E MullerSilvano G Cella
May 1, 1996·Trends in Endocrinology and Metabolism : TEM·X Xu, W E Sonntag
May 16, 2006·Neurobiology of Aging·Boguslawa BaranowskaMagdalena Chmielowska
Jul 23, 1998·The Journal of Veterinary Medical Science·S JuradoC Gomez Dumm
Nov 5, 1998·The Journal of Comparative Neurology·S LealM D Madeira
Nov 22, 1991·The Journal of Comparative Neurology·F de BilbaoM C Senut
Aug 9, 2007·American Journal of Physiology. Endocrinology and Metabolism·Miriam García-San FrutosFranco Sánchez-Franco
Jun 1, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Johannes D VeldhuisCyril Y Bowers
Mar 1, 1991·Journal of the American Geriatrics Society·M Kelijman
Apr 30, 1999·Physiological Reviews·E E MüllerD Cocchi
Jun 1, 1992·Aging : Clinical and Experimental Research·D Cocchi
Jan 1, 1997·Aging : Clinical and Experimental Research·E E MüllerD Cocchi

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