Reduced long-term respiratory morbidity after treatment of respiratory syncytial virus bronchiolitis with ribavirin in previously healthy infants: a preliminary report

Pediatric Pulmonology
D EdellV Khoshoo

Abstract

Previously healthy infants less than 6 months of age with severe respiratory syncytial virus bronchiolitis who required hospitalization were identified from hospital records. Infants had been treated either conservatively (control group, n = 19) or with ribavirin added to conservative management (study group, n = 22). All infants underwent a 1-year follow-up after the initial illness. There was a significant reduction in the prevalence of reactive airway disease in the group treated with ribavirin (P < 0.05) compared with the control group, both in terms of the proportion of patients developing airway reactivity (59% vs. 89%) and the number of episodes of reactive airway disease (31 vs. 70). Our data suggest that ribavirin reduces the prevalence of airway reactivity.

References

Sep 1, 1991·The American Review of Respiratory Disease·G L StropeM M Henry
Sep 1, 1990·The Pediatric Infectious Disease Journal·H R StutmanH K Janaim
Feb 1, 1988·The American Review of Respiratory Disease·K Z VoterF W Henderson
Feb 1, 1987·The Pediatric Infectious Disease Journal·W J RodriguezR H Parrott
Jan 1, 1987·Pediatric Pulmonology·E J DuivermanK F Kerrebijn
Sep 1, 1983·Archives of Disease in Childhood·R L HenryG M Stokes
Apr 1, 1981·The Journal of Pediatrics·D GurwitzH Levison
May 1, 1995·American Journal of Respiratory and Critical Care Medicine·C E LongC B Hall
Oct 1, 1994·The Journal of Infectious Diseases·S GilchristL J Anderson

❮ Previous
Next ❯

Citations

Apr 29, 1998·Pediatric Pulmonology·J T McBride, K M McConnochie
May 1, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Johnson Y N LauZhi Hong
May 1, 2002·Current Opinion in Pulmonary Medicine·Anne Greenough
Oct 14, 2005·Pediatric Case Reviews·Howard B Panitch
Oct 22, 2002·Expert Opinion on Biological Therapy·Leonard R Krilov
Feb 15, 2001·Expert Opinion on Investigational Drugs·G A Prince
Feb 9, 2008·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Chien-Han ChenBor-Luen Chiang
Oct 3, 2003·Expert Opinion on Pharmacotherapy·Simon Broughton, Anne Greenough
Oct 5, 2001·Expert Opinion on Pharmacotherapy·N J Snell
Jan 18, 2003·Paediatric Respiratory Reviews·L BontJ L Kimpen
May 20, 2003·Revista do Hospital das Clínicas·Claudia de Brito Fonseca, Sandra Grisi
Mar 20, 2002·Antiviral Chemistry & Chemotherapy·R C TamZ Hong
Jun 1, 2001·Current Infectious Disease Reports·Leonard R. Krilov
Feb 23, 2018·Infectious Diseases and Therapy·Eric A F SimõesXavier Carbonell-Estrany
Apr 13, 2006·Expert Review of Vaccines·Mohan Pammi Venkatesh, Leonard E Weisman
Aug 3, 2007·Expert Review of Vaccines·Cara K FraserJohn D Hayball
Dec 23, 1999·Current Opinion in Pulmonary Medicine·R S Peebles, T V Hartert
Jun 30, 2006·Antiviral Research·Robert W Sidwell, Dale L Barnard
Nov 1, 2001·Clinical Microbiology Newsletter·Cecile L Tremblay

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.