Reduced neurobehavioral functioning in agricultural workers and rural inhabitants exposed to pesticides in northern Chile and its association with blood biomarkers inhibition

Environmental Health : a Global Access Science Source
Muriel Ramírez-SantanaFloria Pancetti

Abstract

Previous biomonitoring studies have shown that people in the rural population of Coquimbo, the major agricultural area in northern Chile are being occupationally and environmentally exposed to organophosphate/carbamate (OP/CB) pesticides. Given their harmful effects, this study had two aims; first, to evaluate the effect of cumulative or chronic exposure to OP/CB pesticides on the neurobehavioral performance of agricultural workers and rural inhabitants; second, to determine if changes in the neurobehavioral performance are associated to changes in blood biomarkers of OP/CB pesticides during the spray season, when exposure is higher. For the first aim, a cross sectional study of neurobehavioral performance in adult volunteers (men and women, 18-50 years-old, right-handed) was carried out in the pre-spray season. Sampling was done by convenience and a questionnaire was used to categorize participants depending on their level of chronic exposure, as either: occupationally exposed (OE, n = 87), environmentally exposed (EE, n = 81), or non-exposed controls or reference group (RG, n = 100). A neurobehavioral test battery consisting of 21 tests to measure cognitive, motor and emotional state was applied. For the second aim, neurobeha...Continue Reading

References

Nov 8, 1992·The Journal of Comparative Neurology·H TagoH Kimura
Jul 1, 1990·Environmental Health Perspectives·T R Fukuto
Mar 30, 1984·Toxicology and Applied Pharmacology·R J NolanJ H Saunders
Jan 1, 1993·Pharmacology & Therapeutics·T C Marrs
Dec 1, 1996·Human & Experimental Toxicology·T ParrónE Villanueva
Mar 17, 2000·Biochimica Et Biophysica Acta·T FujinoH Yasuda
Apr 20, 2000·Reviews of Environmental Contamination and Toxicology·H N Nigg, J B Knaak
May 15, 2001·Regulatory Toxicology and Pharmacology : RTP·M van GemertM Watson
Dec 31, 2002·Toxicology·Goran A JamalPeter O O Julu
Jun 18, 2003·The Journal of Comparative Neurology·Sultan Darvesh, David A Hopkins
Jun 24, 2003·Occupational and Environmental Medicine·W Kent Anger
Nov 5, 2003·Environmental Health Perspectives·Freya KamelDale P Sandler
Jun 17, 2004·Environmental Health Perspectives·Freya Kamel, Jane A Hoppin
Oct 7, 2004·Biochemical and Biophysical Research Communications·Kei ShimizuKiyomi Kikugawa
Mar 1, 2005·Neurotoxicology and Teratology·Lola Roldán-TapiaFernando Sánchez-Santed
May 13, 2005·Toxicological Sciences : an Official Journal of the Society of Toxicology·Gary B QuistadJohn E Casida
Oct 13, 2006·Neurotoxicology and Teratology·Lola Roldan-TapiaFernando Sanchez-Santed
Dec 22, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Indumathi ManoharanOksana Lockridge
Oct 24, 2008·Environmental Health : a Global Access Science Source·Marina Bjørling-PoulsenPhilippe Grandjean
Mar 17, 2009·Chemical Research in Toxicology·John E Casida
May 24, 2011·Toxicology and Applied Pharmacology·Tesifón ParrónRaquel Alarcón
Jan 24, 2012·Occupational and Environmental Medicine·A A IsmailD S Rohlman
Sep 17, 2013·Environmental Health : a Global Access Science Source·Kimberly YoltonJane C Khoury
Nov 26, 2013·Toxicology Letters·Tesifón ParrónRaquel Alarcón
Feb 25, 2014·Gaceta sanitaria·María Teresa Muñoz-QuezadaMaría Pía Muñoz
Apr 29, 2014·Brain : a Journal of Neurology·Rosebud O Roberts, Ronald C Petersen
Sep 6, 2014·Occupational and Environmental Medicine·Jean StrelitzMatthew C Keifer
Dec 22, 2015·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Diane S RohlmanJames R Olson
Dec 22, 2015·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Fernando Sánchez-SantedElena Herrero Hernández
Feb 26, 2016·Gaceta sanitaria·María Teresa Muñoz-QuezadaAna María Brito
Oct 21, 2016·Environmental Research·Virginia Harrison, Sarah Mackenzie Ross
Dec 23, 2016·International Journal of Environmental Health Research·María Teresa Muñoz-QuezadaMarcos Villalobos
Oct 6, 2017·Environmental Research·Kimberly C PaulBeate Ritz
Jul 12, 2018·The International Journal of Occupational and Environmental Medicine·Suhartono SuhartonoMateus Sakundarno

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