Reduced pregnancy and live birth rates after in vitro fertilization in women with previous Caesarean section: a retrospective cohort study.

Human Reproduction
J VissersJ A F Huirne

Abstract

Does a previous Caesarean section affect reproductive outcomes, including live birth, in women after IVF or ICSI? A previous Caesarean section impairs live birth rates after IVF or ICSI compared to a previous vaginal delivery. Rates of Caesarean sections are rising worldwide. Late sequelae of a Caesarean section related to a niche (Caesarean scar defect) include gynaecological symptoms and obstetric complications. A systematic review reported a lower pregnancy rate after a previous Caesarean section (RR 0.91 CI 0.87-0.95) compared to a previous vaginal delivery. So far, studies have been unable to causally differentiate between problems with fertilisation, and the transportation or implantation of an embryo. Studying an IVF population allows us to identify the effect of a previous Caesarean section on the implantation of embryos in relation to a previous vaginal delivery. We retrospectively studied the live birth rate in women who had an IVF or ICSI treatment at the IVF Centre, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands, between 2006 and 2016 with one previous delivery. In total, 1317 women were included, of whom 334 had a previous caesarean section and 983 had previously delivered vaginally. All secondary inferti...Continue Reading

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Citations

Jul 3, 2020·Human Reproduction·Jolijn VissersJudith Anna Huirne
Oct 14, 2020·Journal of Assisted Reproduction and Genetics·Maria Elisabetta CocciaRita Picone
Oct 11, 2020·Journal of Minimally Invasive Gynecology·Mehmet Resit AsogluMustafa Bahceci
Jun 19, 2021·Gynécologie, Obstétrique, Fertilité & Sénologie·A TorreP Crochet
Aug 11, 2021·Journal of Minimally Invasive Gynecology·Saskia J M Klein MeulemanJudith A F Huirne

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Methods Mentioned

BETA
Caesarean section
pregnancy test
Caesarean sections

Software Mentioned

SPSS

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