Reduced Sleep in the Week Prior to Diagnosis of COVID-19 is Associated with the Severity of COVID-19

Nature and Science of Sleep
Baozhen HuangDiangeng Li

Abstract

The rapid outbreak of coronavirus disease 2019 (COVID-19) is a major health concern, in response to which widespread risk factor research is being carried out. To discover how physical activity and lifestyle affect the epidemic as well as the disease severity and prognosis of COVID-19 patients. This multicenter, retrospective cohort study included 203 adults infected with COVID-19 and 228 uninfected adults in three Chinese provinces, with 164 (80.7%) of the infected participants and 188 (82.5%) of the uninfected participants answering a doctor-administered telephone questionnaire on lifestyle. The binary logistic regression model and the ordinal logit model were used to observe relevance. Comparing sick and non-sick patients, we found that irregular exercise (P=0.004), sedentary lifestyle (P=0.010), and overexertion (P<0.001) may be associated with the susceptibility to COVID-19. In symptomatic patients, using the recommended status as a reference, risk of severe infection increased with decreased sleep status, being 6.729 (95% CI=2.138-21.181) times higher for potentially appropriate sleep (P=0.001) and peaking at 8.612 (95% CI=1.913-38.760) times higher for lack of sleep (P=0.005). Reduction in average daily sleep time signif...Continue Reading

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Citations

Jul 6, 2021·Frontiers in Neuroscience·Allan GiriIsaac Kirubakaran Sundar
Jul 27, 2021·BMJ Nutrition, Prevention & Health·Hyunju KimSara B Seidelmann
Aug 16, 2021·Sleep Medicine·Sushanth Bhat, Sudhansu Chokroverty

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