Reducing adverse effects from UV sunscreens by zeolite encapsulation: comparison of oxybenzone in solution and in zeolites

Photochemistry and Photobiology
Michelle N ChrétienJuan C Scaiano

Abstract

Oxybenzone (OXB) is one of the most widely employed sunscreen ingredients, yet its allowed load is limited to a maximum of 6% reflecting the frequency with which adverse effects are reported. From a spectroscopic point of view, OXB has excellent absorption properties in both the UVB and UVA regions. We propose that zeolite encapsulation can lead to a sunscreen composite ingredient, that we describe as a supramolecular sunscreen, that will retain the excellent spectroscopic properties of OXB, while preventing contact between the skin and the active ingredient. OXB is very photostable, with the only photodegradative pathway observed being the monophotonic photoejection of electrons that leads to trace yields of phenoxyl radicals; this trace reaction is so minor that it cannot be detected from the recovery of unreacted OXB following UV exposure. Solution, as well as powder and in vitro studies of the supramolecular sunscreen, demonstrate that the protective properties of OXB are totally preserved when encapsulated in zeolite NaY.

References

Jan 1, 1990·Archives of Dermatological Research·C SundaramK U Schallreuter
May 2, 1990·Journal of the National Cancer Institute·P L OliveR E Durand
Mar 1, 1988·Experimental Cell Research·N P SinghE L Schneider
Sep 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·R B Setlow
Aug 30, 1984·Biochemical and Biophysical Research Communications·O Ostling, K J Johanson
Jul 1, 1994·The British Journal of Dermatology·P Collins, J Ferguson
Jan 1, 1996·Photochemistry and Photobiology·B A GilchrestM Yaar
Mar 1, 1996·The Journal of Investigative Dermatology·K U SchallreuterH G Edwards
Jan 1, 1996·Journal of Photochemistry and Photobiology. B, Biology·J M AllenS F Allen
Jun 5, 1998·The Australasian Journal of Dermatology·G M HallidayR S Barnetson
Sep 25, 1998·Photochemistry and Photobiology·F P GasparroJ F Nash
Jan 12, 2001·Journal of Photochemistry and Photobiology. B, Biology·T Hancock-Chen, J C Scaiano
Aug 21, 2001·The Journal of Investigative Dermatology·H MaierH Hönigsmann
Mar 21, 2002·The Australasian Journal of Dermatology·N Cook, S Freeman
Mar 29, 2003·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Nick SerponeJincai Zhao
Jun 14, 2003·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Andrea RicciJ C Scaiano
Aug 5, 2003·Canadian Journal of Physiology and Pharmacology·Pascale ReinhardtYvon Deslauriers
Jan 28, 2004·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·Maeran LandersFrances J Storrs
Sep 18, 2004·Cancer Research·Edward C De FaboGlenn Merlino
Sep 10, 2005·Photochemistry and Photobiology·Biao ShenAnn M English
Aug 26, 2006·Photochemistry and Photobiology·Michelle N ChrétienJ C Scaiano
Apr 25, 2007·Critical Reviews in Toxicology·Gerhard J NohynekMichael S Roberts
Aug 19, 2007·Lancet·Stephan LautenschlagerMark R Pittelkow
May 10, 2008·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Marissa SolomonNicholas J Turro

❮ Previous
Next ❯

Citations

Feb 5, 2014·Journal of Photochemistry and Photobiology. B, Biology·Sônia Aparecida FigueiredoMaria José Vieira Fonseca
Mar 6, 2013·Journal of Pharmaceutical Sciences·Valeria AmbrogiMaurizio Ricci
Apr 5, 2011·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Fernanda BerbiczGraciette Matioli
Jan 13, 2015·Expert Opinion on Therapeutic Patents·Mairim R SerafiniLucindo J Quintans-Júnior
Oct 30, 2016·The Journal of Physical Chemistry Letters·Lewis A BakerVasilios G Stavros
Jan 13, 2015·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Marta T IgnasiakTomasz Pedzinski
Feb 14, 2018·PloS One·Aitor UrosaDavid Díez
Aug 11, 2011·Organic & Biomolecular Chemistry·Ali El-Agamey, Shunichi Fukuzumi
Aug 12, 2015·The Journal of Physical Chemistry Letters·Lewis A BakerVasilios G Stavros
Feb 6, 2020·ACS Applied Materials & Interfaces·Jounghyun YooWoosung Kwon

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.